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口吃。右旋苯丙胺与一种镇静剂三氟拉嗪联合治疗的效果。一项非对照研究的初步报告。

Stuttering. The effect of treatment with D-amphetamine and a tranquilizing agent, trifluoperazine. A preliminary report on an uncontrolled study.

作者信息

Fish C H, Bowling E

出版信息

Calif Med. 1965 Nov;103(5):337-9.

PMID:5836893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1516047/
Abstract

In an institution for the mentally retarded, an uncontrolled study was made on the effects of d-amphetamine, d-amphetamine followed by trifluoperazine, and of combined d-amphetamine and trifluoperazine on stuttering. Of 28 patients to whom d-amphetamine was given, 14 showed improvement after one month's treatment. Eight more showed improvement when trifluoperazine was given for one month to those who did not improve on d-amphetamine. In many cases, improvement was sustained at least six months after treatment was discontinued. Treatment with d-amphetamine was apparently more effective in patients with functional than with organic retardation.

摘要

在一所智障机构中,对右旋苯丙胺、先使用右旋苯丙胺再使用三氟拉嗪以及右旋苯丙胺与三氟拉嗪联合使用对口吃的影响进行了一项非对照研究。在接受右旋苯丙胺治疗的28名患者中,14名在治疗一个月后有改善。在接受右旋苯丙胺治疗无改善的患者中,有8名在接受三氟拉嗪治疗一个月后有改善。在许多病例中,治疗停止后改善情况至少持续了六个月。右旋苯丙胺治疗对功能性智障患者显然比对器质性智障患者更有效。

相似文献

1
Stuttering. The effect of treatment with D-amphetamine and a tranquilizing agent, trifluoperazine. A preliminary report on an uncontrolled study.口吃。右旋苯丙胺与一种镇静剂三氟拉嗪联合治疗的效果。一项非对照研究的初步报告。
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Drug-induced stuttering: A comprehensive literature review.药物性口吃:一项全面的文献综述。
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A review of brain circuitries involved in stuttering.口吃相关脑回路综述。
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Memantine-induced speech problems in two patients with autistic disorder.两例自闭症患者因美金刚导致的言语问题。
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本文引用的文献

1
THE USE OF TRANQUILIZERS IN THE TREATMENT OF STUTTERING.安定药在口吃治疗中的应用。
J Speech Hear Disord. 1963 Aug;28:288-94. doi: 10.1044/jshd.2803.288.
2
Effect of amphetamines on speech defects in the mentally retarded.苯丙胺对智力迟钝者言语缺陷的影响。
Calif Med. 1962 Feb;96(2):109-11.
3
An exploratory investigation of the effect of meprobamate on stuttering behavior.眠尔通对口吃行为影响的探索性研究。
J Nerv Ment Dis. 1959 Jun;128(6):558-61.
4
Chlorpromazine in the treatment of neuropsychiatric disorders.氯丙嗪治疗神经精神疾病。
J Am Med Assoc. 1954 May 1;155(1):18-21. doi: 10.1001/jama.1954.03690190024007.
5
The use of dextro-amphetamine in severe behavior problems of children.
South Med J. 1953 Nov;46(11):1124-7. doi: 10.1097/00007611-195311000-00019.