Glasner H
Med Klin. 1976 Apr 23;71(17):703-5.
Cerebrospinal fluid (C.S.F.) findings of 68 patients in multiple sclerosis in relation to the length of illness are reported. Immune reactions in the C.S.F. are similar to those reported by other research workers. In the first 10 years illness an increasing blood-C.S.F. barrier impairment can be noticed. Similar C.S.F.-diagnoses, immune reaction and barrier disturbance, are also possible in acute and severe stages of multiple sclerosis. Consequently, barrier impariment during a severe reaction in the C.S.F. in multiple sclerosis can be an indicator of an increase of pathomorphological C.N.S.-changes which is possible in the first 10 years of illness.
报告了68例多发性硬化症患者的脑脊液（C.S.F.）检查结果与病程长短的关系。脑脊液中的免疫反应与其他研究人员报告的相似。在患病的前10年中，可以注意到血-脑脊液屏障损害不断增加。在多发性硬化症的急性和严重阶段，也可能出现类似的脑脊液诊断、免疫反应和屏障紊乱。因此，多发性硬化症患者脑脊液严重反应期间的屏障损害可能是中枢神经系统病理形态学变化增加的一个指标，这种变化在患病的前10年中是可能出现的。
