Müller R
MMW Munch Med Wochenschr. 1976 May 21;118(21):679-82.
The question whether a hepatitis B virus infection can become chronic as a result of prophylactic or therapeutic measures is investigated. Experience with standard or hepatitis B gamma-globulin has shown no negative influence on the development of chronic hepatitis B virus infections. On the other hand it cannot be excluded that a hepatitis B virus infection may be so modified by steroid therapy, by immunosuppressive or cytostatic treatment that the disease runs a milder course and then tends to chronicity with persistence of HBs antigen.
研究了乙肝病毒感染是否会因预防或治疗措施而转为慢性。标准乙肝球蛋白或乙肝γ球蛋白的使用经验表明,对慢性乙肝病毒感染的发展没有负面影响。另一方面,不能排除类固醇疗法、免疫抑制或细胞抑制治疗可能改变乙肝病毒感染,使疾病病程较轻,随后因乙肝表面抗原持续存在而趋于慢性化。