Thompson J C, Whittaker M
J Clin Pathol. 1965 Nov;18(6):811-2. doi: 10.1136/jcp.18.6.811.
The present evidence indicates that serum pseudocholinesterase activity is increased to about 20% above the normal level in thyrotoxicosis and decreased by about 30% in myxoedema. Treatment restores the esterase level to the average mean activity of random normal as the patient becomes euthyroid. There is no evidence in the present investigation that any of the pseudocholinesterase variants modify these conclusions.
目前的证据表明,甲状腺毒症患者血清假性胆碱酯酶活性比正常水平升高约20%,黏液性水肿患者血清假性胆碱酯酶活性则降低约30%。随着患者甲状腺功能恢复正常,治疗可使酯酶水平恢复至正常人群的平均活性。本次研究中没有证据表明任何假性胆碱酯酶变体改变了这些结论。