11日龄小鼠胚胎的细胞生成周期。
The cell generation cycle of the eleven-day mouse embryo.
作者信息
Atlas M, Bond V P
出版信息
J Cell Biol. 1965 Jul;26(1):19-24. doi: 10.1083/jcb.26.1.19.
Abstract
The incorporation of tritiated thymidine into the DNA of erythroblasts, primitive ependymal cells, and mesenchymal cells of 11-day mouse embryos was studied by radioautography at different times between 25 minutes and 18 hours after injection intraperitoneally. There was no labeling of mitotic figures until 1 hour after injection. Following this, mitotic figures were labeled for about 5.5 hours in primitive ependymal cells and mesenchymal cells, and for a longer period in erythroblasts. The percentage of the labeled primitive ependymal cells at various times after injection indicate a periodic migration into and out of the mitotic zone. The cell generation cycle of primitive ependymal cells and mesenchymal cells is similar to some kinds of adult cells. The cycle of the erythroblasts is more like that of the cells of aging mice.
摘要
通过放射自显影术研究了腹腔注射后25分钟至18小时不同时间点，氚标记胸腺嘧啶核苷掺入11日龄小鼠胚胎的成红细胞、原始室管膜细胞和间充质细胞DNA的情况。注射后1小时前有丝分裂图像无标记。在此之后，原始室管膜细胞和间充质细胞中的有丝分裂图像标记约5.5小时，而成红细胞中的标记时间更长。注射后不同时间标记的原始室管膜细胞百分比表明其有周期性地进出有丝分裂区的迁移。原始室管膜细胞和间充质细胞的细胞生成周期与某些成年细胞相似。成红细胞的周期更类似于衰老小鼠的细胞周期。
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The desoxyribose nucleic acid content of animal nuclei.动物细胞核中的脱氧核糖核酸含量。
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