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牛蛙皮肤电位中细胞内外钠和钾效应之间的相互作用。

Interaction between the effects of inside and outside Na and K on bullfrog skin potential.

作者信息

Leb D E, Edwards C, Lindley B D, Hoshiko T

出版信息

J Gen Physiol. 1965 Nov;49(2):309-20. doi: 10.1085/jgp.49.2.309.

Abstract

The composition of the solution bathing one border of the isolated frog skin affects the response of the potential across the skin to changes in the composition of the solution bathing the opposite border. Increasing the K concentration of the inside (corium) bathing solution decreased the sensitivity of the potential to a change in outside Na concentration. Decreasing the outside Na concentration decreased the sensitivity of the potential to a change in inside K concentration. Increasing the total ionic strength of the outside bathing solution or of both bathing solutions decreased the sensitivity of the potential to a change in outside Na concentration.

摘要

浸泡离体蛙皮一侧边缘的溶液成分,会影响皮肤两侧电位对浸泡另一侧边缘溶液成分变化的反应。增加浸泡内侧(真皮)溶液的钾离子浓度,会降低电位对外部钠离子浓度变化的敏感性。降低外部钠离子浓度,会降低电位对内部钾离子浓度变化的敏感性。增加外部浸泡溶液或两侧浸泡溶液的总离子强度,会降低电位对外部钠离子浓度变化的敏感性。

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本文引用的文献

2
The kinetics of Na24 flux across amphibian skin and bladder.钠-24通过两栖动物皮肤和膀胱的通量动力学。
Acta Physiol Scand. 1960 May 25;49:74-81. doi: 10.1111/j.1748-1716.1960.tb01931.x.
3
FUNCTIONAL ORGANIZATION OF AMPHIBIAN SKIN.两栖动物皮肤的功能组织
Proc Natl Acad Sci U S A. 1964 Apr;51(4):569-77. doi: 10.1073/pnas.51.4.569.
6
ELECTRICAL POTENTIAL PROFILE OF THE TOAD SKIN EPITHELIUM.蟾蜍皮肤上皮的电位分布
J Gen Physiol. 1964 Mar;47(4):795-808. doi: 10.1085/jgp.47.4.795.

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