Leb D E, Edwards C, Lindley B D, Hoshiko T
J Gen Physiol. 1965 Nov;49(2):309-20. doi: 10.1085/jgp.49.2.309.
The composition of the solution bathing one border of the isolated frog skin affects the response of the potential across the skin to changes in the composition of the solution bathing the opposite border. Increasing the K concentration of the inside (corium) bathing solution decreased the sensitivity of the potential to a change in outside Na concentration. Decreasing the outside Na concentration decreased the sensitivity of the potential to a change in inside K concentration. Increasing the total ionic strength of the outside bathing solution or of both bathing solutions decreased the sensitivity of the potential to a change in outside Na concentration.
浸泡离体蛙皮一侧边缘的溶液成分,会影响皮肤两侧电位对浸泡另一侧边缘溶液成分变化的反应。增加浸泡内侧(真皮)溶液的钾离子浓度,会降低电位对外部钠离子浓度变化的敏感性。降低外部钠离子浓度,会降低电位对内部钾离子浓度变化的敏感性。增加外部浸泡溶液或两侧浸泡溶液的总离子强度,会降低电位对外部钠离子浓度变化的敏感性。