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人类前壁心肌梗死期间电活动心肌的丧失。

Loss of electrically active myocardium during anterior infarction in man.

作者信息

Selwyn A P, Ogunro E, Shillingford J P

出版信息

Br Heart J. 1977 Nov;39(11):1186-91. doi: 10.1136/hrt.39.11.1186.

Abstract

A method has been developed of praecordial mapping of changes in R/S ratio and the appearance of Q waves in acute myocardial infarction. Observation of the serial changes in R and Q waves in 40 patients with uncomplicated anterior infarction shows that the loss of electrically active myocardium occurs within 6 hours of the onset of chest pain. Complications, such as recurrent chest pain, associated with extension of myocardial necrosis can be identified and assessed. The total praecordial changes in R/S ratio and Q wave amplitude correlate with the total MB fraction of creatine kinase activity released into the plasma in 20 patients after uncomplicated anterior infarction. This technique for identifying those factors that may modify the progressive loss of active myocardium in the early phase of acute infarction of the heart is noninvasive and repeatable.

摘要

已开发出一种用于胸前区心电图描记急性心肌梗死时R/S比值变化及Q波出现情况的方法。对40例无并发症的前壁梗死患者R波和Q波的系列变化进行观察,结果显示,胸痛发作后6小时内即出现电活动心肌丧失。可以识别和评估与心肌坏死扩展相关的并发症,如复发性胸痛。20例无并发症的前壁梗死后患者,胸前区R/S比值和Q波振幅的总体变化与血浆中释放的肌酸激酶活性的总MB分数相关。这种用于识别可能改变急性心脏梗死早期活性心肌进行性丧失的因素的技术是非侵入性且可重复的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a48/483394/82957d269726/brheartj00237-0028-a.jpg

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Editorial: Assessing myocardial damage in acute infarcts.社论:评估急性梗死中的心肌损伤
N Engl J Med. 1974 Jan 17;290(3):158-9. doi: 10.1056/NEJM197401172900310.

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