原发性高血压患者的代谢与激素研究
Metabolic and hormonal studies in patients with essential hypertension.
作者信息
Januszewicz W, Ciswicka-Sznajderman M, Wocial B, Sznajderman M, Ignatowska-Switalska H, Berent H, Zukowska-Grojec Z, Feltynowski T
出版信息
Br Heart J. 1977 Nov;39(11):1205-9. doi: 10.1136/hrt.39.11.1205.
In 106 patients with essential hypertension and different plasma renin activity several hormonal and metabolic factors were studied: urinary excretion of catecholamines, blood levels of cholesterol and triglycerides, levels of glycaemia and insulinaemia after glucose load and plasma fibrinolytic activity. The plasma renin activity in 46.2 percent of patients was normal, whereas in 25.5 percent it was low, and in 28.3 percent it was high. In patients with high plasma renin activity the excretion of noradrenaline and adrenaline was relatively high while that of dopamine was low. Significantly lower triglyceride levels were found in patients with low plasma renin activity in comparison with those with high and normal plasma renin activity. There was also a statistically significant difference in the euglobulin lysis time which was shorter in patients with low and longest in patients with normal plasma renin activity. The results of the study show that patients with different plasma renin activity may also differ in some hormonal and metabolic values.
对106例原发性高血压且血浆肾素活性不同的患者，研究了几种激素和代谢因素：儿茶酚胺的尿排泄量、胆固醇和甘油三酯的血浓度、葡萄糖负荷后血糖和胰岛素血症水平以及血浆纤维蛋白溶解活性。46.2%患者的血浆肾素活性正常，25.5%患者的血浆肾素活性低，28.3%患者的血浆肾素活性高。血浆肾素活性高的患者中去甲肾上腺素和肾上腺素的排泄量相对较高，而多巴胺的排泄量较低。与血浆肾素活性高和正常的患者相比，血浆肾素活性低的患者甘油三酯水平显著更低。优球蛋白溶解时间也存在统计学显著差异，血浆肾素活性低的患者优球蛋白溶解时间较短，血浆肾素活性正常的患者优球蛋白溶解时间最长。研究结果表明，血浆肾素活性不同的患者在某些激素和代谢值方面也可能存在差异。
Zotero 插件