B16黑色素瘤的克隆形成试验：对环磷酰胺的反应。
Clonogenic assays in the B16 melanoma: response to cyclophosphamide.
作者信息
Steel G G, Adams K, Stephens T C
出版信息
Br J Cancer. 1977 Nov;36(5):618-24. doi: 10.1038/bjc.1977.239.
Abstract
The survival of clonogenic cells in the B16 melanoma has been studied simultaneously by 3 methods: an in vitro assay in soft agar, a lung-colony assay, and the end-point dilution technique. Details of the first 2 methods have previously been reported, but those of the third are described here. The 3 methods have agreed well in investigations of the response of the B16 melanoma to cyclophosphamide.
摘要
通过三种方法同时研究了B16黑色素瘤中克隆形成细胞的存活率：软琼脂中的体外测定法、肺集落测定法和终点稀释技术。前两种方法的详细信息此前已有报道，但第三种方法的详细信息在此处进行描述。在对B16黑色素瘤对环磷酰胺的反应的研究中，这三种方法的结果吻合良好。
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2
The influence of fibrin formation on the transplantability of murine tumour cells: implications for the mechanism of the Révész effect.纤维蛋白形成对小鼠肿瘤细胞移植性的影响：对雷维斯效应机制的启示。
Br J Cancer. 1974 Apr;29(4):279-91. doi: 10.1038/bjc.1974.68.
3
Consideration of the subcutaneously implanted B16 melanoma as a screening model for potential anticancer agents.将皮下植入的B16黑色素瘤作为潜在抗癌药物筛选模型的考量。
Cancer Chemother Rep 2. 1972 Nov;3(1):315-24.
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Transplantation. 1972 Oct;14(4):468-73. doi: 10.1097/00007890-197210000-00011.
5
Stem-cell survival and tumor control in the Lewis lung carcinoma.Lewis肺癌中的干细胞存活与肿瘤控制
Cancer Res. 1975 Jun;35(6):1530-5.
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