Minns R J, Steven F S
Br J Exp Pathol. 1977 Oct;58(5):572-9.
Mechanical tests were conducted on rings of pig thoracic aorta that had been treated with calcium ions to evaluate their effect on aorta media collagen and elastin. There was an increase in stiffness just before rupture and a decrease in storage energy when calcium was introduced into intact rings, but there was no significant difference in mechanical properties when it was introduced into the elastin framework of the media. The calcium was able to bind to the intact aorta media far more readily than to the elastin alone, suggesting that the collagen and muscle framework were far more susceptible to the introduction of calcium than elastin. The calcium content rose along the length of the aorta, as did the collagen content, whilst the elastin content fell, which was also reflected in the change in mechanical properties along the aorta.
对用钙离子处理过的猪胸主动脉环进行了力学测试，以评估其对主动脉中膜胶原蛋白和弹性蛋白的影响。当向完整的主动脉环中引入钙离子时，在破裂前刚度增加，储能减少，但当将钙离子引入中膜的弹性蛋白框架时，力学性能没有显著差异。钙离子与完整的主动脉中膜结合比单独与弹性蛋白结合更容易，这表明胶原蛋白和肌肉框架比弹性蛋白更容易受到钙离子引入的影响。主动脉长度上的钙含量增加，胶原蛋白含量也增加，而弹性蛋白含量下降，这也反映在主动脉沿线力学性能的变化上。
