Mapstone R
Br J Ophthalmol. 1977 Oct;61(10):634-6. doi: 10.1136/bjo.61.10.634.
The outflow changes in 26 eyes were measured during the course of a positive provocative test with pilocarpine and phenylephrine. Three separate patterns of response occurred: (1) One dose of pilocarpine and phenylephrine produced an acute attack with a large reduction in outflow. (2) The first dose of pilocarpine and phenylephrine produced a fall in pressure and increase in outflow. The second dose reversed this effect and closed the angle. (3) The first dose of pilocarpine and phenylephrine increased pressure by an insignificant amount and decreased outflow. The second dose accentuated this response and produced an acute attack.
在使用毛果芸香碱和去氧肾上腺素进行阳性激发试验过程中,对26只眼睛的房水流出情况进行了测量。出现了三种不同的反应模式:(1)一剂毛果芸香碱和去氧肾上腺素引发急性发作,房水流出大幅减少。(2)第一剂毛果芸香碱和去氧肾上腺素使眼压下降,房水流出增加。第二剂则逆转了这种效应并使房角关闭。(3)第一剂毛果芸香碱和去氧肾上腺素使眼压略有升高,房水流出减少。第二剂加剧了这种反应并引发急性发作。