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人类胃部的肥大细胞。

Mast cells of the human stomach.

作者信息

Steer H W

出版信息

J Anat. 1976 Apr;121(Pt 2):385-97.

PMID:58856
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1231807/
Abstract

Mast cells were examined from various sites in the normal human stomach and in the stomachs of patients with gastric ulceration. The distribution of the different types of mast cell granules was determined in the subepithelial region of the normal human stomach. There was a significant difference in this respect between the mast cells at the incisura angularis as compared with those high on the lesser curve or high on the greater curve. Mast cell degranulation (i.e. the shedding of intact granules) and vacuolation were examined with the electron microscope. Degranulation and vacuolation were observed in subepithelial mast cells, whereas only vacuolation was seen in intraepithelial mast cells. The significance of degranulation and vacuolation is discussed.

摘要

对正常人胃的不同部位以及胃溃疡患者的胃进行了肥大细胞检查。测定了正常人胃上皮下区域不同类型肥大细胞颗粒的分布。胃角切迹处的肥大细胞与胃小弯高处或胃大弯高处的肥大细胞在这方面存在显著差异。用电子显微镜检查了肥大细胞脱颗粒（即完整颗粒的脱落）和空泡化情况。上皮下肥大细胞出现了脱颗粒和空泡化，而上皮内肥大细胞仅观察到空泡化。文中讨论了脱颗粒和空泡化的意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/1563782e6070/janat00372-0168-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/3a1e0225fe21/janat00372-0162-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/552f54bc9e8f/janat00372-0164-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/2dcfa4352077/janat00372-0165-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/3082346f7a20/janat00372-0167-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/1563782e6070/janat00372-0168-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/9014eaae2a78/janat00372-0159-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/43d99380f5e6/janat00372-0160-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/a2b3e5073e86/janat00372-0160-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/ef24f78d0c20/janat00372-0161-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/3a1e0225fe21/janat00372-0162-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/1e5778c256de/janat00372-0163-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/552f54bc9e8f/janat00372-0164-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/2dcfa4352077/janat00372-0165-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/1a2cc35ff7e6/janat00372-0166-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/3082346f7a20/janat00372-0167-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/1231807/1563782e6070/janat00372-0168-a.jpg

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1
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J Anat. 1976 Apr;121(Pt 2):385-97.
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引用本文的文献

1
Assay and identification of histamine in human gastric aspirate by a fluorometric--fluoroenzymatic technique. Its application in patients with chronic duodenal ulcer.用荧光-氟酶法测定和鉴定人胃抽吸物中的组胺。其在慢性十二指肠溃疡患者中的应用。
Agents Actions. 1982 Apr;12(1-2):17-25. doi: 10.1007/BF01965100.
2
Mast cell heterogeneity: evidence and implications.肥大细胞的异质性：证据与影响
J Clin Immunol. 1984 Jul;4(4):253-61. doi: 10.1007/BF00915292.
3
Effector cell heterogeneity in immediate hypersensitivity reactions.速发型超敏反应中的效应细胞异质性。

本文引用的文献

1
Electron microscopy of human tissue mast cells.人体组织肥大细胞的电子显微镜检查
JAMA. 1960 Oct 1;174:508-10. doi: 10.1001/jama.1960.63030050006012.
2
Embedding in epoxy resins for ultrathin sectioning in electron microscopy.嵌入环氧树脂用于电子显微镜超薄切片。
Stain Technol. 1960 Nov;35:313-23. doi: 10.3109/10520296009114754.
3
The reaction of peritoneal mast cells in the rat to various activators.大鼠腹膜肥大细胞对各种激活剂的反应。
Clin Rev Allergy. 1983 Sep;1(3):311-25. doi: 10.1007/BF02991223.
4
Tryptase and chymase, markers of distinct types of human mast cells.类胰蛋白酶和糜蛋白酶，不同类型人类肥大细胞的标志物。
Immunol Res. 1989;8(2):130-48. doi: 10.1007/BF02919075.
5
The ultrastructure of mast cells in the uterus throughout the normal menstrual cycle and the postmenopause.整个正常月经周期及绝经后子宫中肥大细胞的超微结构。
J Anat. 1991 Apr;175:51-63.
Acta Pathol Microbiol Scand. 1957;40(4):309-14.
4
Electron and light microscopic identification of the mast cell of the gastrointestinal tract.胃肠道肥大细胞的电子显微镜和光学显微镜鉴定
Gastroenterology. 1969 Feb;56(2):268-79.
5
The effect of compound 48/80 on the rat mast cell.化合物48/80对大鼠肥大细胞的作用。
J Pathol Bacteriol. 1965 Oct;90(2):599-605. doi: 10.1002/path.1700900228.
6
Electron microscope studies on the release of histamine from rat peritoneal mast cells.关于大鼠腹膜肥大细胞组胺释放的电子显微镜研究。
Arch Histol Jpn. 1970 Mar;31(3):393-408. doi: 10.1679/aohc1950.31.393.
7
Mast cells in rat gastrointestinal mucosa. I. Effects of fixation.大鼠胃肠道黏膜中的肥大细胞。I. 固定的影响。
Acta Pathol Microbiol Scand. 1966;66(3):289-302. doi: 10.1111/apm.1966.66.3.289.
8
A study on morphological changes and histamine release induced by compound 48/80 in rat peritoneal mast cells.化合物48/80诱导大鼠腹腔肥大细胞形态变化及组胺释放的研究。
Exp Cell Res. 1965 Dec;40(3):637-54. doi: 10.1016/0014-4827(65)90241-7.
9
The response of mast cells to compound 48/80 studied with the electron microscope.用电子显微镜研究肥大细胞对化合物48/80的反应。
Lab Invest. 1965 Oct;14(10):1744-63.