Lo J P, Svehag S E, Gorham J R
Acta Vet Scand. 1965;6(4):341-52. doi: 10.1186/BF03547091.
The sensitivity and error limits of a conventional neutralization test for antibody to distemper virus were compared with the same parameters of a single dilution-probit test for neutralizing antibody. With the former test, antibody was demonstrable in ferrets 8 days following a single subcutaneous injection of virus while probit analysis of data from the single dilution test revealed the appearance of antibody as early as 4 days post-immunization. The error terms of the single dilution test were relatively large as compared to those of the conventional test for antibody. Distinctly biphasic antibody responses were observed in ferrets following a single subcutaneous injection of distemper virus.
将犬瘟热病毒抗体常规中和试验的敏感性和误差限度与中和抗体单一稀释-概率单位试验的相同参数进行了比较。在前一种试验中，雪貂单次皮下注射病毒后8天可检测到抗体，而对单一稀释试验数据的概率单位分析显示，免疫后4天抗体就已出现。与抗体常规试验相比，单一稀释试验的误差项相对较大。雪貂单次皮下注射犬瘟热病毒后，观察到明显的双相抗体反应。
