Gerrard J W, Ko C G, Dalgleish R, Tan L K
Clin Exp Immunol. 1977 Sep;29(3):447-56.
Serum-immunoglobulin levels (IgG, IgM, IgA, IgD, IgE) have been studied in white and metis (Cree Indian) communities in Saskatchewan. The levels of IgG, IgA, IgD and IgE were higher in the metis than in the whites. Both IgG and IgM were higher in females than in males. IgG and IgA levels rose progressively with age. IgM levels rose rapidly during the first year to almost adult levels, and then fell gradually after the age of 30. IgE levels also rose rapidly during the first 3 years of life, were higher on average in children than in adults, and fell to adult levels at puberty. Low levels of IgA were associated with high levels of IgG; they were not associated with either high levels of IgE or an increase in the prevalence of asthma.
在萨斯喀彻温省的白人社区和梅蒂斯人(克里印第安人)社区对血清免疫球蛋白水平(IgG、IgM、IgA、IgD、IgE)进行了研究。梅蒂斯人的IgG、IgA、IgD和IgE水平高于白人。女性的IgG和IgM水平高于男性。IgG和IgA水平随年龄增长而逐渐升高。IgM水平在第一年迅速上升至几乎成人水平,然后在30岁后逐渐下降。IgE水平在生命的前3年也迅速上升,儿童的平均水平高于成人,并在青春期降至成人水平。低水平的IgA与高水平的IgG相关;它们与高水平的IgE或哮喘患病率的增加均无关。