大鼠IgE的产生。I. 抗原剂量对初次和再次反应素抗体应答的影响。
Rat IgE production. I. Effect of dose of antigen on primary and secondary reaginic antibody responses.
作者信息
Jarrett E E, Stewart D C
出版信息
Immunology. 1974 Sep;27(3):365-81.
Abstract
The experiments described here form part of a series carried out to determine the conditions of antigen presentation which dispose to the production of IgE antibody in the rat. We have found that Hooded Lister rats in comparison with rats of some other strains have an exceptional ability to produce reaginic antibodies: responses can be consistently induced with very small doses of antigen and are boosted to high levels with a second dose of antigen. The effect of the dose of antigen on these responses is as follows.
摘要
此处描述的实验是为确定有利于大鼠产生 IgE 抗体的抗原呈递条件而开展的一系列实验的一部分。我们发现，与其他一些品系的大鼠相比，Hooded Lister 大鼠产生反应素抗体的能力格外强：用非常小剂量的抗原就能持续诱导出反应，且用第二剂抗原可将反应增强到很高水平。抗原剂量对这些反应的影响如下。
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