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大鼠IgE的产生。I. 抗原剂量对初次和再次反应素抗体应答的影响。

Rat IgE production. I. Effect of dose of antigen on primary and secondary reaginic antibody responses.

作者信息

Jarrett E E, Stewart D C

出版信息

Immunology. 1974 Sep;27(3):365-81.

PMID:4547289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1445613/
Abstract

The experiments described here form part of a series carried out to determine the conditions of antigen presentation which dispose to the production of IgE antibody in the rat. We have found that Hooded Lister rats in comparison with rats of some other strains have an exceptional ability to produce reaginic antibodies: responses can be consistently induced with very small doses of antigen and are boosted to high levels with a second dose of antigen. The effect of the dose of antigen on these responses is as follows.

摘要

此处描述的实验是为确定有利于大鼠产生 IgE 抗体的抗原呈递条件而开展的一系列实验的一部分。我们发现,与其他一些品系的大鼠相比,Hooded Lister 大鼠产生反应素抗体的能力格外强:用非常小剂量的抗原就能持续诱导出反应,且用第二剂抗原可将反应增强到很高水平。抗原剂量对这些反应的影响如下。

相似文献

1
Rat IgE production. I. Effect of dose of antigen on primary and secondary reaginic antibody responses.大鼠IgE的产生。I. 抗原剂量对初次和再次反应素抗体应答的影响。
Immunology. 1974 Sep;27(3):365-81.
2
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J Immunol. 1972 Mar;108(3):834-6.
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J Immunol. 1974 Sep;113(3):824-9.

引用本文的文献

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Anaphylactic release of intestinal goblet cell mucus.肠道杯状细胞黏液的过敏反应性释放。
Immunology. 1980 Feb;39(2):173-8.
3
Mucosal immunology.黏膜免疫学
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Specific and total IgE responses to antigenic stimuli in Brown-Norway, Lewis and Sprague-Dawley rats.棕色挪威大鼠、刘易斯大鼠和斯普拉格-道利大鼠对抗原刺激的特异性和总IgE反应。
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Genetic differences in immune exclusion and partial tolerance to ingested antigens.免疫排斥及对摄入抗原的部分耐受性中的基因差异。
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IgE suppression by maternal IgG.母体IgG对IgE的抑制作用。
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Effect of antigen load on development of milk antibodies in infants allergic to milk.抗原负荷对牛奶过敏婴儿体内牛奶抗体产生的影响。
Br Med J (Clin Res Ed). 1981 Sep 12;283(6293):693-6. doi: 10.1136/bmj.283.6293.693.
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Immunological responses to complex salts of platinum. II. Enhanced IgE antibody responses to ovalbumin with concurrent administration of platinum salts in the rat.对铂复合盐的免疫反应。II. 大鼠同时给予铂盐时对卵清蛋白的IgE抗体反应增强。
Clin Exp Immunol. 1984 Nov;58(2):478-85.
10
Adjuvants in the induction and enhancement of rat IgE responses.诱导和增强大鼠IgE反应中的佐剂。
Clin Exp Immunol. 1980 Jan;39(1):183-9.

本文引用的文献

1
THE MECHANISM OF ANAPHYLAXIS. I. PRODUCTION AND BIOLOGICAL PROPERTIES OF 'MAST CELL SENSITIZING' ANTIBODY.过敏反应的机制。I. “肥大细胞致敏”抗体的产生及生物学特性。
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THE PRODUCTION OF ANAPHYLACTIC ANTIBODY IN THE RAT.大鼠体内过敏抗体的产生
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A comparison of the immunologic and physiologic responses of normal and allergic individuals.正常个体与过敏个体免疫和生理反应的比较。
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Persistent formation of reagins in mice injected with low doses of ovalbuminl.在注射低剂量卵清蛋白的小鼠中持续形成反应素。
Immunology. 1971 Jul;21(1):11-5.
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Suppression of reagin synthesis in rabbits by passively administered antibody.通过被动给予抗体抑制兔体内反应素的合成。
Immunology. 1970 May;18(5):775-85.
6
Potentiated reagin response to egg albumin and conalbumin in Nippostrongylus brasiliensis infected rats.巴西日圆线虫感染大鼠对卵清蛋白和伴清蛋白的致敏反应增强
Life Sci. 1969 Oct 15;8(20):1073-7. doi: 10.1016/0024-3205(69)90459-7.
7
Potentiation of reaginic (IgE) antibody to ovalbumin in the rat following sequential trematode and nematode infections.大鼠先后感染吸虫和线虫后,对卵清蛋白的反应素性(IgE)抗体增强。
Immunology. 1972 Jun;22(6):1099-101.
8
Infectious immunological tolerance.感染性免疫耐受
Immunology. 1971 Dec;21(6):903-14.
9
Potentiated reagin response: initiation with minute doses of antigen and alum followed by infection with Nippostrongylus brasiliensis.增强反应素反应:先用微量抗原和明矾引发,随后感染巴西日圆线虫。
J Immunol. 1973 Jan;110(1):197-204.
10
Reaginic antibody formation in the mouse. I. Antibody-mediated suppression of reaginic antibody formation.小鼠中反应素抗体的形成。I. 抗体介导的反应素抗体形成抑制。
J Immunol. 1972 Jul;109(1):84-9.