Kumar P, Bartram C I
Gastrointest Radiol. 1979 Aug 15;4(3):285-9. doi: 10.1007/BF01887539.
Significant changes on a standard barium follow-through examination in celiac disease have been determined by comparison with functional changes (irritable bowel syndrome), malabsorption without a villous lesion (chronic pancreatitis), and a villous abnormality without malabsorption (dermatitis herpetiformis). Patients with iron deficiency anemia formed the control group. Slight jejunal dilatation (26-30 mm) was found in 15% of the celiacs and 17% of the irritable bowel patients. Dilatation in excess of 30 mm and/or effacement of jejunal fold pattern occurred only with an abnormal jejunal biopsy, in 54% of the celiacs and 33% of the dermatitis herpetiformis patients. Patients with malabsorption by itself and 46% of the celiacs could not be distinguished from those with irritable bowel syndrome. The concept of a malabsorption pattern is considered invalid, and the diagnosis of celiac disease can be reliably established only by peroral jejunal biopsy.
通过与功能性改变(肠易激综合征)、无绒毛病变的吸收不良(慢性胰腺炎)以及无吸收不良的绒毛异常(疱疹样皮炎)进行比较,已确定了乳糜泻患者在标准钡剂通过检查中的显著变化。缺铁性贫血患者作为对照组。在15%的乳糜泻患者和17%的肠易激综合征患者中发现轻度空肠扩张(26 - 30毫米)。仅在空肠活检异常时出现超过30毫米的扩张和/或空肠皱襞形态消失,在54%的乳糜泻患者和33%的疱疹样皮炎患者中出现。仅存在吸收不良的患者以及46%的乳糜泻患者无法与肠易激综合征患者区分开来。吸收不良模式的概念被认为是无效的,乳糜泻的诊断只能通过经口空肠活检可靠地确立。