Sugai T, Takahashi Y, Takagi T
Contact Dermatitis. 1977 Oct;3(5):249-56. doi: 10.1111/j.1600-0536.1977.tb03670.x.
Patch tests and photopatch tests with various cosmetics, coal tar dyes, perfumes, lanolin preparations and parabens-mix were performed in 53 patients with pigmented cosmetic dermatitis similar in clinical appearance to Riehl's melanosis. The results showed that coal tar dyes, particularly brilliant lake red R, were closely related to the cause of the disease. In patch testing and photopatch testing with coal tar dyes, the incidence of positive responses to the brilliant lake red R was found to be significantly higher than that to the other coal tar colors (22/38 = 57.9%). The relevance of ultraviolet light to the disease was found to be much less than the ratio expected (14/47 = 29.8%). A high incidence of positive responses to fragrances was also found, but it is considered to play a secondary role in the etiology of the disease.
对53例临床表现与里尔氏黑变病相似的色素沉着性化妆品皮炎患者，进行了各种化妆品、煤焦油染料、香水、羊毛脂制剂和对羟基苯甲酸酯混合物的斑贴试验和光斑贴试验。结果表明，煤焦油染料，尤其是亮湖红R，与该病的病因密切相关。在用煤焦油染料进行斑贴试验和光斑贴试验时，发现对亮湖红R的阳性反应发生率显著高于其他煤焦油色素（22/38 = 57.9%）。发现紫外线与该病的相关性远低于预期比例（14/47 = 29.8%）。还发现对香料的阳性反应发生率较高，但认为其在该病的病因学中起次要作用。
