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婴儿肾活检标本的电子显微镜研究。

Electron microscopic study of infantile renal biopsy specimens.

作者信息

Kádár A, Molnár E, Bucsky P, Láncos F, Jellinek H

出版信息

Exp Pathol (Jena). 1977 Sep-Oct;14(3-4):189-203. doi: 10.1016/s0014-4908(77)80066-5.

DOI:10.1016/s0014-4908(77)80066-5
PMID:590422
Abstract

Out of 54 open renal biopsies performed on children, 17 were selected and studied not only by light microscopy but also by electron microscopy. Statistical-mathematical analysis of basement membrane thickness-measurements was carried out. It is concluded that electron microscopic investigation of the renal biopsy material is required in selected cases involving diagnostic or therapeutic problems. In nephrotic syndrome it may help above all to separate minimal changes from early forms or glomerular lesion of the focal sclerosing type. Electron microscopy can also be useful in any of the mono- and oligosymptomatic renal diseases. In those cases only electron microscopy makes it possible to provide exact morphological diagnosis which is necessary to the proper therapy.

摘要

在对儿童进行的54例开放性肾活检中,选取了17例进行研究,不仅进行了光学显微镜检查,还进行了电子显微镜检查。对基底膜厚度测量结果进行了统计数学分析。得出的结论是,在涉及诊断或治疗问题的特定病例中,需要对肾活检材料进行电子显微镜检查。在肾病综合征中,它首先有助于将微小病变与局灶性硬化型的早期形式或肾小球病变区分开来。电子显微镜在任何单症状和少症状性肾脏疾病中也可能有用。在这些情况下,只有电子显微镜才能提供准确的形态学诊断,而这对于正确的治疗是必要的。

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