[13C] - 特殊富集的四肽胃泌素及相关化合物的合成与某些特性
Synthesis and some characteristics of [13C]-specially enriched tetragastrin and the related compound.
作者信息
Yamada S, Sakagami M, Yanaihara N, Nishikawa H, Watari H
出版信息
Experientia. 1977 Dec 15;33(12):1566-7. doi: 10.1007/BF01933999.
PMID:590436
Abstract
[13C]-enriched tetragastrin and the related compound were synthesized in solution. Conversion of S-[13C]methylated tetragastrin to the enriched tetragastrin gave 10.5 ppm upfield chemical shift of Cepsilon resonance. The potency of the synthetic tetragastrin to stimulate gastric acid secretion was virtually identical with that of pentagastrin (ICI).
摘要
[13C]富集的四肽胃泌素及相关化合物在溶液中合成。S-[13C]甲基化四肽胃泌素转化为富集的四肽胃泌素后，Cε共振的化学位移在高场方向有10.5 ppm的变化。合成的四肽胃泌素刺激胃酸分泌的效力与五肽胃泌素（ICI）几乎相同。
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