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Studies on digitalis. 13. A comparison of the effects of potassium on the inotropic and arrhythmia-producing actions of ouabain.

作者信息

Williams J F, Klocke F J, Braunwald E

出版信息

J Clin Invest. 1966 Mar;45(3):346-52. doi: 10.1172/JCI105349.

DOI:10.1172/JCI105349
PMID:5904552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC292704/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/818c/292704/6ee8a2e64bc8/jcinvest00261-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/818c/292704/b2d20fe460ad/jcinvest00261-0078-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/818c/292704/6ee8a2e64bc8/jcinvest00261-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/818c/292704/b2d20fe460ad/jcinvest00261-0078-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/818c/292704/6ee8a2e64bc8/jcinvest00261-0079-a.jpg

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1
Studies on digitalis. 13. A comparison of the effects of potassium on the inotropic and arrhythmia-producing actions of ouabain.洋地黄研究。13. 钾对哇巴因正性肌力作用和致心律失常作用影响的比较。
J Clin Invest. 1966 Mar;45(3):346-52. doi: 10.1172/JCI105349.
2
A study of combined effects of ouabain and potassium on the dog heart in situ.哇巴因与钾对在位犬心脏联合作用的研究。
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引用本文的文献

1
The influence of reduced serum potassium level on the toxicity of some cardenolides in guinea pigs.血清钾水平降低对豚鼠某些强心苷毒性的影响。
Basic Res Cardiol. 1981 Jan-Feb;76(1):62-78. doi: 10.1007/BF01908163.
2
New concepts of digitalis.洋地黄的新概念。
Calif Med. 1969 Dec;111(6):423-32.
3
Antiarrhythmic agents. II. Therapeutic considerations.抗心律失常药物。II. 治疗方面的考虑。

本文引用的文献

1
STUDIES ON DIGITALIS. IX. EFFECTS OF OUABAIN ON THE NONFAILING HUMAN HEART.洋地黄研究。IX. 哇巴因对正常人类心脏的作用。
J Clin Invest. 1963 Jul;42(7):1105-11. doi: 10.1172/JCI104796.
2
Effects of cardiac glycosides upon the electrical activity of single ventricular fibers of the frog heart, and their relation to the digitalis effect of the electrocardiogram.强心苷对蛙心单个心室纤维电活动的影响及其与心电图洋地黄效应的关系。
Circulation. 1952 Aug;6(2):172-82. doi: 10.1161/01.cir.6.2.172.
3
The action of several cardiac glycosides on conduction velocity and ventricular excitability in the dog heart.
Drugs. 1973;5(4):292-317. doi: 10.2165/00003495-197305040-00003.
4
The effects of diphenylhydantoin and potassium on the biological activity of ouabain in the guinea-pig heart.二苯乙内酰脲和钾对豚鼠心脏中哇巴因生物活性的影响。
Br J Pharmacol. 1973 Jan;47(1):85-96. doi: 10.1111/j.1476-5381.1973.tb08161.x.
5
Digitalis use in acute myocardial infarction: current concepts.洋地黄在急性心肌梗死中的应用：当前概念
Can Med Assoc J. 1974 Sep 21;111(6):561, 563-4.
6
Extrarenal actions of aldosterone antagonists in guinea pigs. II. Reduction of the toxicity of beta-methyl-digoxin.醛固酮拮抗剂在豚鼠体内的肾外作用。II. β-甲基地高辛毒性的降低。
Naunyn Schmiedebergs Arch Pharmacol. 1973;279(1):9-18. doi: 10.1007/BF00502063.
7
Reduction of the equilibrium binding of cardiac glycosides and related compounds to Na+,K+-ATPase as a possible mechanism for the potassium-induced reversal of their toxicity.强心苷及相关化合物与钠钾ATP酶平衡结合的减少，可能是钾诱导其毒性逆转的一种机制。
Naunyn Schmiedebergs Arch Pharmacol. 1978 Sep;304(2):157-65. doi: 10.1007/BF00495552.
几种强心苷对犬心脏传导速度和心室兴奋性的作用。
Circulation. 1951 Nov;4(5):729-34. doi: 10.1161/01.cir.4.5.729.
4
Some effects of digoxin on the heart and circulation in man; digoxin in enlarged hearts not in clinical congestive failure.地高辛对人体心脏和循环系统的某些作用；地高辛在未出现临床充血性心力衰竭的扩大心脏中的作用
Circulation. 1951 Sep;4(3):366-77. doi: 10.1161/01.cir.4.3.366.
5
A nomogram for cardiac contractility involving calcium, potassium and digitalis-like drugs.一种涉及钙、钾和洋地黄类药物的心脏收缩力列线图。
Am J Physiol. 1951 Jun;165(3):520-6. doi: 10.1152/ajplegacy.1951.165.3.520.
6
The effects of potassium, ammonium, calcium, strontium and magnesium on the electrogram and myogram of mammalian heart muscle.钾、铵、钙、锶和镁对哺乳动物心肌电描记图和肌动描记图的影响。
J Pharmacol Exp Ther. 1951 Apr;101(4):317-26.
7
Digitalis, electrolytes and the surgical patient.洋地黄、电解质与外科手术患者
Am J Cardiol. 1960 Aug;6:309-37. doi: 10.1016/0002-9149(60)90320-9.
8
PROBLEMS IN THE USE OF DIGITALIS IN THE MANAGEMENT OF CONGESTIVE HEART FAILURE.洋地黄在充血性心力衰竭治疗中的应用问题
Prog Cardiovasc Dis. 1965 Jan;7:360-86. doi: 10.1016/s0033-0620(65)80027-5.
9
THE EFFECT OF DESLANOSIDE ON THE DURATION OF THE PHASES OF VENTRICULAR SYSTOLE IN MAN.去乙酰毛花苷对人体心室收缩各期时长的影响。
Am J Cardiol. 1965 Feb;15:153-61. doi: 10.1016/0002-9149(65)90449-2.
10
THE ACTIONS OF CARDIAC GLYCOSIDES ON HEART MUSCLE CELLS.强心苷对心肌细胞的作用。
Circulation. 1964 Aug;30:237-51. doi: 10.1161/01.cir.30.2.237.