山梨醇途径：存在于神经和脊髓中，在糖尿病时会有底物蓄积。
Sorbitol pathway: presence in nerve and cord with substrate accumulation in diabetes.
作者信息
Gabbay K H, Merola L O, Field R A
出版信息
Science. 1966 Jan 14;151(3707):209-10. doi: 10.1126/science.151.3707.209.
PMID:5907911
Abstract
Glucose, sorbitol, fructose, and inositol are present in peripheral nerve and spinal cord. Marked elevation of these substances occurs in these tissues in mildly diabetic animals. These alterations provide biochemical mechanisms which could be significant in the etiology of diabetic neuropathy.
摘要
葡萄糖、山梨醇、果糖和肌醇存在于周围神经和脊髓中。在轻度糖尿病动物的这些组织中，这些物质会显著升高。这些变化提供了可能在糖尿病神经病变病因学中具有重要意义的生化机制。
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