Whitmore G F, Gulyas S
Science. 1966 Feb 11;151(3711):691-4. doi: 10.1126/science.151.3711.691.
Short exposures of mammalian cells to tritiated thymidine of high specific activity destroys the proliferative capacity of mammalian cells. Since the killing is limited to cells that have synthesized DNA in the presence of the labeled compound, an exposure duration of less than one generation can yield a synchronized population.
将高比活度的氚标记胸腺嘧啶核苷短时间暴露于哺乳动物细胞，会破坏其增殖能力。由于这种杀伤作用仅限于在标记化合物存在时已合成DNA的细胞，所以暴露时间少于一个细胞世代就可以产生同步化群体。
