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比较解毒作用。无脊椎动物对芳香酸的解毒作用:蝎子中胍丁胺缀合物的检测。

Comparative detoxication. The detoxication of aromatic acids by invertebrates: detection of agmatine conjugates in scorpions.

作者信息

Hitchcock M, Smith J N

出版信息

Biochem J. 1966 Mar;98(3):736-41. doi: 10.1042/bj0980736.

DOI:10.1042/bj0980736
PMID:5911522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1264914/
Abstract
  1. Benzoic acid and p-nitrobenzoic acid were converted in the scorpion Palamnaeus into N(1)-benzoylagmatine and N(1)-p-nitrobenzoylagmatine. 2. Some benzoyl- and p-nitrobenzoyl-arginine were also formed and these compounds were probable precursors of the agmatine derivatives. 3. p-Nitrobenzoyl- and p-aminobenzoyl-arginine were formed in millipedes dosed with the aromatic acids. 4. Woodlice excreted p-amino- and p-nitro-benzoic acid as their glycine conjugates and no conjugation could be found in the crab Gecarcinus and a freshwater crayfish Astacus.
摘要
  1. 苯甲酸和对硝基苯甲酸在蝎子(Palemnaeus)体内被转化为N(1)-苯甲酰胍丁胺和N(1)-对硝基苯甲酰胍丁胺。2. 还形成了一些苯甲酰基-和对硝基苯甲酰基-精氨酸,这些化合物可能是胍丁胺衍生物的前体。3. 给千足虫投喂芳香酸后,形成了对硝基苯甲酰基-和对氨基苯甲酰基-精氨酸。4. 潮虫将对氨基苯甲酸和对硝基苯甲酸作为它们的甘氨酸共轭物排出,而在螃蟹(Gecarcinus)和淡水小龙虾(Astacus)中未发现共轭现象。

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引用本文的文献

1
Detoxications in peripatus. Sulphate, phosphate and histidine conjugations.栉蚕的解毒作用。硫酸盐、磷酸盐和组氨酸结合反应。
Biochem J. 1970 Jun;118(1):1-8. doi: 10.1042/bj1180001.
2
Water-soluble metabolites of p-nitrophenol and 1-naphthyl N-methylcarbamate in flies and grass grubs. Formation of glucose phosphate and phosphate conjugates.果蝇和草地蛴螬中对硝基苯酚和1-萘基N-甲基氨基甲酸酯的水溶性代谢产物。磷酸葡萄糖和磷酸共轭物的形成。
Biochem J. 1974 Nov;144(2):303-10. doi: 10.1042/bj1440303.

本文引用的文献

1
Detoxications of aromatic acids with glutamic acid and arginine in spiders.蜘蛛中芳香酸与谷氨酸和精氨酸的解毒作用
Nature. 1962 Jul 28;195:399-400. doi: 10.1038/195399a0.
2
Comparative detoxication. 7. The metabolism of chlorobenzene in locusts: excretion of unchanged chlorobenzene and cysteine conjugates.比较解毒作用。7. 蝗虫体内氯苯的代谢:未变化氯苯和半胱氨酸共轭物的排泄。
Biochem J. 1960 Apr;75(1):165-72. doi: 10.1042/bj0750165.
3
Comparative detoxication. 5. Conjugation of aromatic acids in reptiles: formation of ornithuric acid, hippuric acid and glucuronides.比较解毒作用。5. 爬行动物中芳香酸的结合作用:鸟尿酸、马尿酸和葡糖醛酸苷的形成。
Biochem J. 1958 Aug;69(4):509-16. doi: 10.1042/bj0690509.
4
Comparative detoxication. 13. Detoxication of aromatic acids in arachnids: arginine, glutamic acid and glutamine conjugations.比较解毒作用。13. 蛛形纲动物中芳香酸的解毒作用:精氨酸、谷氨酸和谷氨酰胺结合作用。
Biochem J. 1964 Nov;93(2):392-400. doi: 10.1042/bj0930392.
5
Comparative detoxication. 9. The metabolism of some halogenated compounds by conjugation with glutathione in the locust.比较解毒作用。9. 蝗虫中某些卤代化合物与谷胱甘肽结合的代谢过程。
Biochem J. 1964 Mar;90(3):449-56. doi: 10.1042/bj0900449.