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比较解毒作用。无脊椎动物对芳香酸的解毒作用:蝎子中胍丁胺缀合物的检测。

Comparative detoxication. The detoxication of aromatic acids by invertebrates: detection of agmatine conjugates in scorpions.

作者信息

Hitchcock M, Smith J N

出版信息

Biochem J. 1966 Mar;98(3):736-41. doi: 10.1042/bj0980736.

Abstract
  1. Benzoic acid and p-nitrobenzoic acid were converted in the scorpion Palamnaeus into N(1)-benzoylagmatine and N(1)-p-nitrobenzoylagmatine. 2. Some benzoyl- and p-nitrobenzoyl-arginine were also formed and these compounds were probable precursors of the agmatine derivatives. 3. p-Nitrobenzoyl- and p-aminobenzoyl-arginine were formed in millipedes dosed with the aromatic acids. 4. Woodlice excreted p-amino- and p-nitro-benzoic acid as their glycine conjugates and no conjugation could be found in the crab Gecarcinus and a freshwater crayfish Astacus.
摘要
  1. 苯甲酸和对硝基苯甲酸在蝎子(Palemnaeus)体内被转化为N(1)-苯甲酰胍丁胺和N(1)-对硝基苯甲酰胍丁胺。2. 还形成了一些苯甲酰基-和对硝基苯甲酰基-精氨酸,这些化合物可能是胍丁胺衍生物的前体。3. 给千足虫投喂芳香酸后,形成了对硝基苯甲酰基-和对氨基苯甲酰基-精氨酸。4. 潮虫将对氨基苯甲酸和对硝基苯甲酸作为它们的甘氨酸共轭物排出,而在螃蟹(Gecarcinus)和淡水小龙虾(Astacus)中未发现共轭现象。

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