栉蚕的解毒作用。硫酸盐、磷酸盐和组氨酸结合反应。
Detoxications in peripatus. Sulphate, phosphate and histidine conjugations.
作者信息
Jordan T W, McNaught R W, Smith J N
出版信息
Biochem J. 1970 Jun;118(1):1-8. doi: 10.1042/bj1180001.
Abstract
Phenols were detoxified in the Onycophoran Peripatoides novaezealandiae by conjugation with sulphuric acid and phosphoric acid, but no evidence for a glycoside detoxication could be found. [(14)C]Benzoic acid was metabolized in 24h to N(2)-benzoyl-l-histidine, which was identified by electrophoresis, chromatography and dilution analysis. Similar conjugates were formed with p-aminobenzoic acid and p-nitrobenzoic acid. In longer-duration experiments further unidentified metabolites were formed, two of which appeared to result from the further metabolism of the histidine conjugate.
摘要
酚类物质在新西兰栉蚕（Peripatoides novaezealandiae）中通过与硫酸和磷酸结合进行解毒，但未发现糖苷解毒的证据。[¹⁴C]苯甲酸在24小时内代谢为N₂-苯甲酰基-L-组氨酸，通过电泳、色谱和稀释分析进行了鉴定。对氨基苯甲酸和对硝基苯甲酸也形成了类似的结合物。在更长时间的实验中形成了更多未鉴定的代谢产物，其中两种似乎是组氨酸结合物进一步代谢的结果。
相似文献
1
Detoxications in peripatus. Sulphate, phosphate and histidine conjugations.栉蚕的解毒作用。硫酸盐、磷酸盐和组氨酸结合反应。
Biochem J. 1970 Jun;118(1):1-8. doi: 10.1042/bj1180001.
2
Acidic conjugate of phenols in insects; glucoside phosphate and glucoside sulphate derivatives.昆虫中酚类的酸性共轭物；磷酸葡糖苷和硫酸葡糖苷衍生物。
Xenobiotica. 1983 Jun;13(6):383-9. doi: 10.3109/00498258309052276.
3
Comparative detoxication. The detoxication of aromatic acids by invertebrates: detection of agmatine conjugates in scorpions.比较解毒作用。无脊椎动物对芳香酸的解毒作用：蝎子中胍丁胺缀合物的检测。
Biochem J. 1966 Mar;98(3):736-41. doi: 10.1042/bj0980736.
4
Comparative detoxication. 13. Detoxication of aromatic acids in arachnids: arginine, glutamic acid and glutamine conjugations.比较解毒作用。13. 蛛形纲动物中芳香酸的解毒作用：精氨酸、谷氨酸和谷氨酰胺结合作用。
Biochem J. 1964 Nov;93(2):392-400. doi: 10.1042/bj0930392.
5
The conjugation of phenols with phosphate in grass grubs and flies.草蛴螬和苍蝇中酚类与磷酸盐的结合作用。
Biochem J. 1967 Apr;103(1):42-8. doi: 10.1042/bj1030042.
6
Conjugation and excretion of the amino and acetamido benzoic acids.氨基苯甲酸和乙酰氨基苯甲酸的结合与排泄。
Am J Physiol. 1959 Jun;196(6):1224-30. doi: 10.1152/ajplegacy.1959.196.6.1224.
7
Kinetic studies of the metabolism of foreign organic compounds. IV. The conjugation of phenols with sulphuric acid.外来有机化合物代谢的动力学研究。IV. 酚类与硫酸的结合反应
Biochem J. 1952 Nov;52(3):419-23. doi: 10.1042/bj0520419.
8
The metabolism of gamma-2,3,4,5,6-pentachlorocyclohex-1-ene and gamma-hexachlorocyclohexane in rats.大鼠体内γ-2,3,4,5,6-五氯环己-1-烯和γ-六氯环己烷的代谢
Biochem J. 1965 Aug;96(2):521-5. doi: 10.1042/bj0960521.
9
p-Alkyl-Benzoyl-CoA Conjugates as Relevant Metabolites of Aromatic Aldehydes With Rat Testicular Toxicity-Studies Leading to the Design of a Safer New Fragrance Chemical.p-烷基苯甲酰基辅酶 A 缀合物作为芳香醛具有睪丸毒性的相关代谢物 - 设计更安全新香料的研究。
Toxicol Sci. 2017 Dec 1;160(2):244-255. doi: 10.1093/toxsci/kfx178.
10
The metabolism of foreign compounds in the cestode, Moniezia expansa, and the nematode, Ascaris lumbricoides var suum.扩展莫尼茨绦虫和猪蛔虫这两种寄生虫对外源化合物的代谢。
Xenobiotica. 1975 May;5(5):279-92. doi: 10.3109/00498257509052062.
引用本文的文献
1
The metabolism of 3,5-di-tert.-butylphenyl N-methylcarbamate in insects and by mouse liver enzymes.3,5-二叔丁基苯基N-甲基氨基甲酸酯在昆虫体内及小鼠肝脏酶作用下的代谢
Biochem J. 1971 Nov;125(2):395-400. doi: 10.1042/bj1250395.
2
Metabolism of m-tert.-butylphenyl N-methylcarbamate in insects and mice.间叔丁基苯基N-甲基氨基甲酸酯在昆虫和小鼠体内的代谢
Biochem J. 1971 Nov;125(2):385-93. doi: 10.1042/bj1250385.
本文引用的文献
1
Studies in detoxication. 82. The fate of benzoic acid in some domestic and other birds.解毒作用的研究。82. 苯甲酸在一些家禽及其他鸟类体内的代谢情况。
Biochem J. 1960 Sep;76(3):595-600. doi: 10.1042/bj0760595.
2
Comparative detoxication. 5. Conjugation of aromatic acids in reptiles: formation of ornithuric acid, hippuric acid and glucuronides.比较解毒作用。5. 爬行动物中芳香酸的结合作用：鸟尿酸、马尿酸和葡糖醛酸苷的形成。
Biochem J. 1958 Aug;69(4):509-16. doi: 10.1042/bj0690509.
3
Comparative detoxication. 4. Ethereal sulphate and glucoside conjugations in insects.比较解毒作用。4. 昆虫体内的硫酸酯和糖苷结合作用
Biochem J. 1955 Jul;60(3):436-42. doi: 10.1042/bj0600436.
4
The conjugation of phenols with phosphate in grass grubs and flies.草蛴螬和苍蝇中酚类与磷酸盐的结合作用。
Biochem J. 1967 Apr;103(1):42-8. doi: 10.1042/bj1030042.
5
Oxidation of methyl groups by grass grubs and vertebrate liver enzymes.草地蛴螬和脊椎动物肝脏酶对甲基的氧化作用。
Biochem J. 1967 Feb;102(2):504-10. doi: 10.1042/bj1020504.
6
Comparative detoxication. The detoxication of aromatic acids by invertebrates: detection of agmatine conjugates in scorpions.比较解毒作用。无脊椎动物对芳香酸的解毒作用：蝎子中胍丁胺缀合物的检测。
Biochem J. 1966 Mar;98(3):736-41. doi: 10.1042/bj0980736.
7
Comparative detoxication. 11. Conjugations of 1-naphthol and some other phenols in houseflies and locusts.比较解毒作用。11. 家蝇和蝗虫中1-萘酚及其他一些酚类的结合反应
Biochem J. 1964 Jul;92(1):127-31. doi: 10.1042/bj0920127.
8
Comparative detoxication. 13. Detoxication of aromatic acids in arachnids: arginine, glutamic acid and glutamine conjugations.比较解毒作用。13. 蛛形纲动物中芳香酸的解毒作用：精氨酸、谷氨酸和谷氨酰胺结合作用。
Biochem J. 1964 Nov;93(2):392-400. doi: 10.1042/bj0930392.
9
Comparative detoxication. 9. The metabolism of some halogenated compounds by conjugation with glutathione in the locust.比较解毒作用。9. 蝗虫中某些卤代化合物与谷胱甘肽结合的代谢过程。
Biochem J. 1964 Mar;90(3):449-56. doi: 10.1042/bj0900449.
10
The isolation and identification of 2,3-dihydroxybenzoic acid and 2-N,6-N-di-92,3-dihydroxybenzoyl)-L-lysine formed by iron-deficient Azotobacter vinelandii.由缺铁的棕色固氮菌形成的2,3 - 二羟基苯甲酸和2 - N,6 - N - 二 -（2,3 - 二羟基苯甲酰基）- L - 赖氨酸的分离与鉴定
Biochemistry. 1969 Mar;8(3):757-62. doi: 10.1021/bi00831a002.
Zotero 插件