膳食抗体与心肌梗死

Dietary antibodies and myocardial infarction.

作者信息

Scott B B, Swinburne M L, McGuffin P, Losowsky M S

出版信息

Lancet. 1976 Jul 17;2(7977):125-6. doi: 10.1016/s0140-6736(76)92848-8.

Abstract

Serum milk, egg, and gluten antibody titres were measured in ninety men with acute myocardial infarction and compared with those of thirty-six age-matched male controls. None of the antibody titres was higher in the patients with myocardial infarction, nor was there a significant correlation between antibody titres and the Norris prognostic index or death before hospital discharge. The results do not support the suggestion that immunological mechanisms are involved in the pathogenesis of coronary heart-disease and atherosclerosis.

摘要

对90名急性心肌梗死男性患者测定了血清中牛奶、鸡蛋和麸质抗体滴度，并与36名年龄匹配的男性对照组进行了比较。心肌梗死患者的抗体滴度均未更高，抗体滴度与诺里斯预后指数或出院前死亡之间也无显著相关性。这些结果不支持免疫机制参与冠心病和动脉粥样硬化发病机制的观点。