小鼠伤寒中的宿主-寄生虫关系。
Host-parasite relations in mouse typhoid.
作者信息
Mackaness G B, Blanden R V, Collins F M
出版信息
J Exp Med. 1966 Oct 1;124(4):573-83. doi: 10.1084/jem.124.4.573.
Abstract
The development of acquired resistance to Salmonella typhimurium has been studied in mice infected intravenously with small numbers of streptomycin-sensitive or streptomycin-resistant organisms. By the 14th day of a primary infection the mouse develops a mechanism capable of destroying completely a super infecting dose of organisms, but is unable to eliminate organisms of the primary infection. The latter are constantly returned to the circulation from necrotic foci at the sites of implantation. Passive transfer of serum from actively infected or vaccinated animals, and immunization with heat-killed organisms, increase the capacity of the host to clear organisms from the blood, but do not interfere to any significant extent with their subsequent multiplication in the tissues. It is concluded that the resistance of actively infected animals depends on a nonhumoral mechanism capable of destroying organisms from endogenous or exogenous sources.
摘要
已经在静脉内感染少量链霉素敏感或链霉素抗性鼠伤寒沙门氏菌的小鼠中研究了获得性耐药性的发展。在初次感染的第14天，小鼠形成了一种能够完全破坏超感染剂量细菌的机制，但无法清除初次感染的细菌。后者不断从植入部位的坏死灶返回循环系统。来自主动感染或接种疫苗动物的血清的被动转移以及用热灭活细菌进行免疫，可增加宿主从血液中清除细菌的能力，但在很大程度上不会干扰它们随后在组织中的繁殖。得出的结论是，主动感染动物的抗性取决于一种能够破坏内源性或外源性细菌的非体液机制。
相似文献
1
Host-parasite relations in mouse typhoid.小鼠伤寒中的宿主-寄生虫关系。
J Exp Med. 1966 Oct 1;124(4):573-83. doi: 10.1084/jem.124.4.573.
2
Mechanisms of acquired resistance in mouse typhoid.小鼠伤寒获得性耐药机制。
J Exp Med. 1966 Oct 1;124(4):585-600. doi: 10.1084/jem.124.4.585.
3
4
Studies of immunity in typhoid fever. Protection induced by killed oral antigens or by primary infection.伤寒热免疫研究。口服灭活抗原或初次感染诱导的保护作用。
Bull World Health Organ. 1971;44(5):667-72.
5
Studies on experimental typhoid: bacterial multiplication and host cell response after infection with Salmonella enteritidis in mice immunized with live and killed vaccines.实验性伤寒研究：用活疫苗和死疫苗免疫的小鼠感染肠炎沙门氏菌后的细菌增殖及宿主细胞反应
Jpn J Microbiol. 1959 Apr;3:231-42. doi: 10.1111/j.1348-0421.1959.tb00119.x.
6
A contribution to the laboratory assay of typhoid vaccines.对伤寒疫苗实验室检测的一项贡献。
Bull World Health Organ. 1962;26(3):381-8.
7
On the variation mutabile type (murase) originated from routh phase of salmonellae. II. Influences of immunization with attenuated mutabile variant or killed R type organisms against experimental typhoid of mice caused by rough variant.关于源自沙门氏菌粗糙型阶段的变异可变型（murase）。二、用减毒变异型或灭活R型菌免疫对粗糙变异型所致小鼠实验性伤寒的影响。
Jpn J Med Sci Biol. 1952 Aug;5(4):195-213. doi: 10.7883/yoken1952.5.195.
8
9
Mechanism of the protective immunity against murine typhoid: persistence of Salmonella L forms in the liver after immunization with live-cell vaccines.小鼠伤寒保护性免疫机制：活细胞疫苗免疫后肝脏中沙门氏菌L型的持续存在。
FEMS Microbiol Immunol. 1992 Oct;5(4):191-9. doi: 10.1111/j.1574-6968.1992.tb05901.x.
10
Cross-reactive gut-directed immune response against Salmonella enterica serovar Paratyphi A and B in typhoid fever and after oral Ty21a typhoid vaccination.肠靶向交叉免疫反应对伤寒和口服 Ty21a 伤寒疫苗接种后血清型 A 和 B 沙门氏菌的影响。
Vaccine. 2012 Sep 14;30(42):6047-53. doi: 10.1016/j.vaccine.2012.07.051. Epub 2012 Aug 2.
引用本文的文献
1
Antibodies and Protection in Systemic Infections: Do We Still Have More Questions than Answers?全身性感染中的抗体和保护作用：我们是否仍有更多的疑问而非答案？
Infect Immun. 2020 Sep 18;88(10). doi: 10.1128/IAI.00219-20.
2
The effects of vaccination and immunity on bacterial infection dynamics in vivo.疫苗接种和免疫对体内细菌感染动态的影响。
PLoS Pathog. 2014 Sep 18;10(9):e1004359. doi: 10.1371/journal.ppat.1004359. eCollection 2014 Sep.
3
Vaccines against invasive Salmonella disease: current status and future directions.抗侵袭性沙门氏菌病疫苗：现状与未来方向
Hum Vaccin Immunother. 2014;10(6):1478-93. doi: 10.4161/hv.29054. Epub 2014 May 7.
4
Probing the ArcA regulon under aerobic/ROS conditions in Salmonella enterica serovar Typhimurium.在鼠伤寒沙门氏菌有氧/ROS 条件下探测 ArcA 调控子。
BMC Genomics. 2013 Sep 17;14:626. doi: 10.1186/1471-2164-14-626.
5
Importance of antibody and complement for oxidative burst and killing of invasive nontyphoidal Salmonella by blood cells in Africans.抗体和补体对非伤寒型侵袭性沙门氏菌在非洲人群血细胞中氧化爆发和杀伤的重要性。
Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3070-5. doi: 10.1073/pnas.0910497107. Epub 2010 Jan 28.
6
Salmonella enterica serovar Typhimurium mutants completely lacking the F(0)F(1) ATPase are novel live attenuated vaccine strains.鼠伤寒沙门氏菌血清型 Typhimurium 的 F(0)F(1) ATP 酶完全缺失突变株是新型活减毒疫苗株。
Vaccine. 2010 Jan 22;28(4):940-9. doi: 10.1016/j.vaccine.2009.10.146. Epub 2009 Dec 3.
7
Inhibition of Salmonella enterica serovar typhimurium motility and entry into epithelial cells by a protective antilipopolysaccharide monoclonal immunoglobulin A antibody.一种具有保护作用的抗脂多糖单克隆免疫球蛋白A抗体对鼠伤寒沙门氏菌运动性及进入上皮细胞的抑制作用
Infect Immun. 2008 Sep;76(9):4137-44. doi: 10.1128/IAI.00416-08. Epub 2008 Jul 14.
8
Induction of Resistance by Listeria monocytogenes Cell Wall Fraction.李斯特菌细胞壁成分诱导的抗性。
Infect Immun. 1974 Nov;10(5):1163-9. doi: 10.1128/iai.10.5.1163-1169.1974.
9
Immunity in Experimental Salmonellosis I. Protection Induced by Rough Mutants of Salmonella typhimurium.实验性沙门氏菌病的免疫反应 I. 鼠伤寒沙门氏菌粗糙突变体引起的保护作用。
Infect Immun. 1970 Sep;2(3):309-15. doi: 10.1128/iai.2.3.309-315.1970.
10
Oral Immunization in Experimental Salmonellosis II. Characteristics of the Immune Response to Temperature-Sensitive Mutants Given by Oral and Parenteral Routes.口服免疫在实验性沙门氏菌病中的作用 II. 经口服和肠道外途径给予温度敏感突变体后的免疫应答特征。
Infect Immun. 1970 Aug;2(2):183-91. doi: 10.1128/iai.2.2.183-191.1970.
本文引用的文献
1
Interaction between Salmonella enteritidis and tissue cultured macrophages derived from immunized animals.肠炎沙门氏菌与源自免疫动物的组织培养巨噬细胞之间的相互作用。
Jpn J Microbiol. 1960 Oct;4:395-407. doi: 10.1111/j.1348-0421.1960.tb00188.x.
2
PARTIAL PURIFICATION OF THE "PROTECTIVE" ANTIGEN OF SALMONELLA TYPHIMURIUM AND ITS DISTRIBUTION AMONGST VARIOUS STRAINS OF BACTERIA.鼠伤寒沙门氏菌“保护性”抗原的部分纯化及其在不同菌株间的分布
Aust J Exp Biol Med Sci. 1965 Feb;43:65-78. doi: 10.1038/icb.1965.5.
3
THE BASIS FOR IMMUNITY TO MOUSE TYPHOID. 3. CELL-BOUND ANTIBODY.小鼠伤寒免疫的基础。3. 细胞结合抗体。
Aust J Exp Biol Med Sci. 1964 Apr;42:237-48. doi: 10.1038/icb.1964.25.
4
BASIS FOR IMMUNITY TO TYPHOID IN MICE AND THE QUESTION OF "CELLULAR IMMUNITY".小鼠对伤寒免疫的基础及“细胞免疫”问题
Bacteriol Rev. 1963 Dec;27(4):391-404. doi: 10.1128/br.27.4.391-404.1963.
5
Genetic effects in nonspecific resistance to infectious disease.传染病非特异性抵抗力中的遗传效应。
Bacteriol Rev. 1960 Mar;24(1):192-200. doi: 10.1128/br.24.1.192-200.1960.
6
The effect of antibody on intracellular parasitism of Salmonella typhimurium in mononuclear phagocytes in vitro: prolonged survival of infected monocytes in presence of antibody.抗体对体外单核吞噬细胞中鼠伤寒沙门氏菌细胞内寄生的影响：在有抗体存在的情况下，被感染单核细胞的存活时间延长。
J Exp Med. 1959 Nov 1;110(5):715-30. doi: 10.1084/jem.110.5.715.
7
Experimental salmonellosis. Intracellular growth of Salmonella enteritidis ingested in mononuclear phagocytes of mice, and cellular basis of immunity.实验性沙门氏菌病。小鼠单核吞噬细胞摄取肠炎沙门氏菌后的细胞内生长及免疫的细胞基础。
J Bacteriol. 1961 Jun;81(6):863-8. doi: 10.1128/jb.81.6.863-868.1961.
8
Resistance to reinfection in experimental mouse typhoid.实验性小鼠伤寒中的再感染抗性
J Hyg (Lond). 1957 Sep;55(3):334-43. doi: 10.1017/s0022172400037244.
9
Some hypotheses on the aetiology of fatal infections in partially resistant hosts and their application to mice challenged with Salmonella paratyphi-B or Salmonella typhimurium by intraperitoneal injection.关于部分抗性宿主中致命感染病因的一些假说及其在经腹腔注射副伤寒沙门氏菌B或鼠伤寒沙门氏菌攻击的小鼠中的应用。
J Gen Microbiol. 1957 Feb;16(1):38-58. doi: 10.1099/00221287-16-1-38.
10
Mechanisms of acquired resistance in mouse typhoid.小鼠伤寒获得性耐药机制。
J Exp Med. 1966 Oct 1;124(4):585-600. doi: 10.1084/jem.124.4.585.
Zotero 插件