Beck I T, Hernandez N A, Solymar J
Can Med Assoc J. 1966 Nov 5;95(19):941-6.
One of the characteristic motor abnormalities in achalasia of the esophagus is the lack of relaxation of the lower esophageal sphincter during swallowing. In a subject with a clinical history and radiologic evidence of early achalasia all the typical motor abnormalities of the disease were observed in the course of pressure studies, but the sphincter exhibited a fall of pressure in response to a contraction of the body of the esophagus. This relaxation occurred later than would be expected in the normal esophagus and, therefore, this unusual condition was named dyschalasia.The relationship of dyschalasia to classical achalasia is discussed and several theories are advanced. The authors believe that dyschalasia is possibly an early stage of achalasia.
食管贲门失弛缓症的典型运动异常之一是吞咽时食管下括约肌缺乏松弛。在一名有早期贲门失弛缓症临床病史和放射学证据的受试者中,在压力研究过程中观察到了该疾病所有典型的运动异常,但括约肌在食管体部收缩时出现压力下降。这种松弛比正常食管预期的时间要晚,因此,这种异常情况被命名为吞咽困难。本文讨论了吞咽困难与典型贲门失弛缓症的关系,并提出了几种理论。作者认为吞咽困难可能是贲门失弛缓症的早期阶段。