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[食管贲门失弛缓症伴下括约肌明显正常松弛:临床意义及对气囊扩张术的治疗反应]

[Esophageal achalasia with apparently normal relaxation of the lower sphincter: clinical significance and therapeutic response to pneumatic dilatation].

作者信息

Garrigues Gil V, Ponce García J, Pertejo Pastor V, Gálvez Castillo C, Valverde de la Osa J, Berenguer Lapuerta J

机构信息

Servicio de Medicina Digestiva, Hospital, La Fe, Valencia.

出版信息

Rev Esp Enferm Dig. 1996 Aug;88(8):529-32.

PMID:8962756
Abstract

OBJECTIVE

To evaluate if the clinical presentation and the response to pneumatic dilation is different in patients with achalasia with an apparent normal lower esophageal sphincter relaxation.

DESIGN

Prospective study to compare clinical, radiographic and manometric characteristics and the response to pneumatic dilation according to the ability of the lower esophageal sphincter to relax normally.

PATIENTS

One hundred and fifty seven consecutive patients with achalasia were included. Relaxation of the lower esophageal sphincter was abnormal in 130 patients and apparently normal in 27. The response to pneumatic dilation was evaluated in 116 patients, 94 with abnormal function of the lower esophageal sphincter and 22 with normal function.

RESULTS

Clinical findings, esophageal diameter and basal pressure of the lower esophageal sphincter were similar in both groups. The efficacy of the dilation, the number of dilations and the rate of complications were also similar.

CONCLUSIONS

Patients with achalasia and an apparent normal lower esophageal sphincter relaxation are not different from patients with typical achalasia and present a similar response to pneumatic dilation.

摘要

目的

评估食管下括约肌松弛明显正常的贲门失弛缓症患者的临床表现及对气囊扩张的反应是否存在差异。

设计

前瞻性研究,根据食管下括约肌正常松弛的能力,比较临床、影像学和测压特征以及对气囊扩张的反应。

患者

纳入157例连续的贲门失弛缓症患者。130例患者食管下括约肌松弛异常,27例明显正常。对116例患者进行了气囊扩张反应评估,其中94例食管下括约肌功能异常,22例功能正常。

结果

两组的临床发现、食管直径和食管下括约肌基础压力相似。扩张疗效、扩张次数和并发症发生率也相似。

结论

食管下括约肌松弛明显正常的贲门失弛缓症患者与典型贲门失弛缓症患者无差异,对气囊扩张的反应相似。

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Rev Esp Enferm Dig. 1996 Aug;88(8):529-32.
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