用于胰腺癌诊断的计算机断层扫描

Computerised axial tomography for diagnosis of pancreatic cancer.

作者信息

Wiggans G, Schein P S, MacDonald J S, Schellinger D, Harbert J

出版信息

Lancet. 1976 Jul 31;2(7979):233-5. doi: 10.1016/s0140-6736(76)91030-8.

Abstract

Computerised axial tomography demonstrated the presence of a mass lesion in the pancreas in 9 (64%) of 14 patients with histologically confirmed pancreatic cancer. Since this was a retrospective analysis, the percentage of false positive and negative results using this technique is not as yet known. The technique appears accurate in detecting abnormal pancreatic masses of 10 cm in diameter or more, however, for masses less than 10 cm in diameter the yield at present is only 33%. With further technical refinement to increase resolution, the automatic computerised transverse axial scan should prove to be an invaluable procedure for the detection of pancreatic carcinoma, in designing radiation therapy ports, and in providing objective information regarding response of therapy and progression of disease.

摘要

计算机断层扫描显示，在14例经组织学确诊为胰腺癌的患者中，有9例（64%）胰腺存在占位性病变。由于这是一项回顾性分析，目前尚不清楚使用该技术的假阳性和假阴性结果的百分比。该技术在检测直径10厘米或更大的胰腺异常肿块方面似乎很准确，然而，对于直径小于10厘米的肿块，目前的检出率仅为33%。随着进一步的技术改进以提高分辨率，自动计算机断层扫描在检测胰腺癌、设计放射治疗野以及提供有关治疗反应和疾病进展的客观信息方面应被证明是一种非常有价值的方法。