塞姆利基森林病毒衣壳蛋白与核糖体的短暂关联。
Transient association of Semliki Forest virus capsid protein with ribosomes.
作者信息
Söderlund H, Ulmanen I
出版信息
J Virol. 1977 Dec;24(3):907-9. doi: 10.1128/JVI.24.3.907-909.1977.
Abstract
HeLa cells infected with Semliki Forest virus were exposed to [35S]methionine for 1 min and chased for various periods. The analysis of labeled ribonucleoproteins showed that the viral capsid protein associated first with the large ribosomal subunit in polysomes, from which it was chased to assembling nucleocapsids and to free monosomes.
摘要
用Semliki森林病毒感染的HeLa细胞暴露于[35S]甲硫氨酸1分钟，然后进行不同时间段的追踪。对标记的核糖核蛋白的分析表明，病毒衣壳蛋白首先与多核糖体中的大核糖体亚基结合，随后从该亚基被追踪到正在组装的核衣壳和游离的单核糖体。
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