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拟交感神经药和抗交感神经药在青光眼治疗中的应用(作者译)

[Sympathomimetic and sympatholytic drugs in the therapy of glaucoma (author's transl)].

出版信息

Klin Monbl Augenheilkd. 1977 Oct;171(4):538-46.

PMID:592644
Abstract

The basis of sympathetic impulse transmission are summarised. Sympathomimetics and sympatholytics are discussed with regard to their mode of action, clinical use and contra-indications. We found that a 1% solution of adrenaline twice a day together with miotics is most suitable for long-term treatment. With the beta-blockers Bupranolol and Timolol tried by us can a massive pressure reduction be obtained, but which is of short duration with the concentrations used up till now. Adrenergic potentiators can not be recommended.

摘要

总结了交感神经冲动传递的基础。讨论了拟交感神经药和抗交感神经药的作用方式、临床用途及禁忌证。我们发现,1%的肾上腺素溶液每日两次联合缩瞳剂最适合长期治疗。使用我们试验过的β受体阻滞剂布普洛尔和噻吗洛尔可实现大幅降压,但就目前使用的浓度而言,降压持续时间较短。不推荐使用肾上腺素能增效剂。

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引用本文的文献

1
The IOP-lowering effect of timolol in simple and capsular glaucoma. A multicenter study in Finland.
Graefes Arch Clin Exp Ophthalmol. 1982;218(2):83-7. doi: 10.1007/BF02153716.
2
Interaction of timolol and adrenaline.噻吗洛尔与肾上腺素的相互作用。
Br J Ophthalmol. 1981 Jan;65(1):53-5. doi: 10.1136/bjo.65.1.53.

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