Eyckmans L, Hook E W
J Bacteriol. 1966 Mar;91(3):997-1003. doi: 10.1128/jb.91.3.997-1003.1966.
Eyckmans, Luc (Cornell University Medical College, New York, N.Y.), and Edward W. Hook. Induction of penicillinase by staphylococci in vitro and in vivo. J. Bacteriol. 91:997-1003. 1966.-Staphylococci in mice with peritoneal infection showed no significant increase in penicillinase activity 6 hr after administration of penicillin G. In contrast, induction of penicillinase was readily demonstrated in leukopenic animals under similar conditions. Induction of penicillinase by staphylococci in vitro was inhibited by including leukocytes and immune serum in the mixtures. The role of leukocytes in inhibiting induction of penicillinase by staphylococci in response to penicillin was investigated.
艾克曼斯，卢克（纽约州纽约市康奈尔大学医学院），以及爱德华·W·胡克。葡萄球菌在体内外对青霉素酶的诱导作用。《细菌学杂志》91:997 - 1003。1966年。——腹腔感染小鼠体内的葡萄球菌在给予青霉素G 6小时后，青霉素酶活性无显著增加。相比之下，在类似条件下，白细胞减少的动物中很容易证明青霉素酶的诱导作用。在混合物中加入白细胞和免疫血清可抑制葡萄球菌在体外对青霉素酶的诱导作用。研究了白细胞在抑制葡萄球菌对青霉素产生的青霉素酶诱导反应中的作用。
