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右旋糖酐用于预防术后血栓栓塞(作者译)

[Dextran for the prophylaxis of postoperative thromboembolism (author's transl)].

作者信息

Rahmer H

出版信息

Langenbecks Arch Chir. 1977 Nov;345:365-9. doi: 10.1007/BF01305504.

Abstract

Dextran has a well-documented antithrombotic effect that is due to a reduction in platelet adhesions, increased lysability of thrombi, and improved blood flow. Anaphylactoid reactions may occur during the first 30--50 ccm of dextran infusion. They have an incidence of 1:80000 during anesthesia. The main advantage of dextran prophylaxis is the lack of bleeding complications. It is extremely effective in lowering the incidence of lethal pulmonary embolisms.

摘要

右旋糖酐具有充分记录的抗血栓形成作用,这归因于血小板黏附减少、血栓溶解性增加以及血流改善。在输注30 - 50立方厘米右旋糖酐期间可能发生类过敏反应。在麻醉期间其发生率为1:80000。右旋糖酐预防的主要优点是缺乏出血并发症。它在降低致死性肺栓塞的发生率方面极其有效。

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