Flemming F, Thomas E, Widera R
Zentralbl Chir. 1976;101(10):577-85.
Only anti-coagulators and aggregation-stoppers may be said to be the medicamental prophylaxis of thromboembolism. The Cumarin-Indandion group is burdened with continuous laboratory controls. Contraindications excluding a general prophylaxis for this group as well as for Heparin and ASS exist. Infukoll, which is virtually always applicable, has the disadvantage that it has to be infused. Heparin- and Dextranspreparations however can already be used preoperatively, which means that a further decline of the coagulation complications can be expected.
只有抗凝剂和聚集抑制剂可被视为血栓栓塞的药物预防措施。香豆素 - 茚满二酮类药物需要持续的实验室监测。对于该类药物以及肝素和乙酰水杨酸存在排除一般预防的禁忌症。几乎总能适用的羟乙基淀粉有必须静脉输注的缺点。然而肝素和右旋糖酐制剂术前就可使用,这意味着凝血并发症有望进一步减少。