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[新生儿的葡萄糖。一项动力学研究(作者译)]

[Glucose in the newborn. A kinetic study (author's transl)].

作者信息

Stock G J, Gladtke E

出版信息

Monatsschr Kinderheilkd (1902). 1977 Nov;125(11):935-7.

PMID:593280
Abstract

At birth, serum glucose concentration in the newborn is correlated to the maternal glucose level. In the following hours glucose concentration declines to a low level and remains there for some days. Intravenous glucose loading five hours after delivery leads to a decrease of the glucose level in the same pattern as is found immediately after birth. Compared to older children the turnover rate of glucose in the newborn is reduced. Therefore the decrease of serum glucose concentration immediately after birth cannot be explained by an increased glucose consumption. At birth there is a stop of the glucose supply via the umbilical cord. The results show that the decreasing glucose concentration after birth can be explained as an adaptation of the steady state from the higher maternal level to a lower newborn level.

摘要

出生时,新生儿的血清葡萄糖浓度与母体葡萄糖水平相关。在接下来的几个小时里,葡萄糖浓度会降至较低水平并持续数天。分娩后五小时静脉注射葡萄糖会导致葡萄糖水平以与出生后立即观察到的相同模式下降。与年龄较大的儿童相比,新生儿的葡萄糖周转率较低。因此,出生后血清葡萄糖浓度的下降不能用葡萄糖消耗增加来解释。出生时,通过脐带的葡萄糖供应停止。结果表明,出生后葡萄糖浓度的下降可以解释为从较高的母体水平到较低的新生儿水平的稳态适应。

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