High rate of endoreduplications and chromosomal aberrations in hamster cells treated with sodium nitrite in vitro.
作者信息
Tsuda H, Kato K
出版信息
Mutat Res. 1977 Sep;56(1):69-74. doi: 10.1016/0027-5107(77)90243-3.
PMID:593296
Abstract
As shown by results in this paper, NaNO2 induced endoreduplications and chromosomal aberrations as well as malignant transformation, in hamster cells in vitro, although the carcinogenic action of NaNO2 has not been reported in animals. The mode of action of NaNO2 in mammalian cells requires further investigation.
摘要
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