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与主动脉瘤相关的凝血病。

The coagulopathy associated with aortic aneurysms.

作者信息

Gétaz E P, Louw J H

出版信息

Postgrad Med J. 1977 Nov;53(625):668-71. doi: 10.1136/pgmj.53.625.668.

DOI:10.1136/pgmj.53.625.668
PMID:593992
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2496824/
Abstract

The authors in this article record their experience with eight-four patients with abdominal aortic aneurysms. Twenty-seven patients (32%) presented with ruptured aneurysms with an overall mortality of 56%. Of the unruptured aneurysms, 67% were operable with a mortality of 5.3%. The highest mortality amongst the patients with ruptured aneurysms was in the group who was shocked. In the group with ruptured aneurysms, of those in whom platelet counts were performed, 50% were abnormally low, and 56% had evidence of abnormal coagulation. Seventy per cent of those with coagulation abnormalities died. In the unruptured group 28.2% had thrombocytopenia but no other abnormalities of coagulation. All patients undergoint aneurysm resection should have a platelet count and a full clotting screen. Therapy should be directed to normalization of the coagulation system.

摘要

本文作者记录了他们对84例腹主动脉瘤患者的治疗经验。27例(32%)患者为动脉瘤破裂,总体死亡率为56%。在未破裂的动脉瘤中,67%适合手术,死亡率为5.3%。破裂动脉瘤患者中死亡率最高的是休克组。在破裂动脉瘤组中,进行血小板计数的患者中,50%血小板计数异常低,56%有凝血异常证据。有凝血异常的患者中70%死亡。在未破裂组中,28.2%有血小板减少症,但无其他凝血异常。所有接受动脉瘤切除术的患者都应进行血小板计数和全面的凝血筛查。治疗应致力于使凝血系统恢复正常。

相似文献

1
The coagulopathy associated with aortic aneurysms.与主动脉瘤相关的凝血病。
Postgrad Med J. 1977 Nov;53(625):668-71. doi: 10.1136/pgmj.53.625.668.
2
Preoperative coagulopathy in ruptured abdominal aortic aneurysm predicts poor outcome.腹主动脉瘤破裂患者的术前凝血功能障碍预示着预后不良。
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Survivors of ruptured abdominal aortic aneurysm: the iceberg's tip.腹主动脉瘤破裂幸存者:冰山一角。
Br Med J. 1977 Oct 22;2(6094):1055-7. doi: 10.1136/bmj.2.6094.1055.
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Descending thoracic aneurysm rupture with a known abdominal aortic aneurysm.降主动脉瘤破裂合并已知腹主动脉瘤
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Abdominal aortic aneurysm resection in patients more than 80 years old.80岁以上患者的腹主动脉瘤切除术
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Twenty-one years' experience with ruptured abdominal aortic aneurysms.
Surg Gynecol Obstet. 1975 Dec;141(6):859-62.
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Ruptured abdominal aortic aneurysms.腹主动脉瘤破裂
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A review of 12 years' experience in the surgical management of 198 ruptured and unruptured aneurysms of the abdominal aorta.对198例腹主动脉瘤破裂和未破裂病例进行外科治疗的12年经验回顾。
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引用本文的文献

1
Is the size of an abdominal aortic aneurysm associated with coagulopathy?腹主动脉瘤的大小与凝血病有关吗?
World J Surg. 2005 Jul;29(7):925-9; discussion 929. doi: 10.1007/s00268-005-7718-z.

本文引用的文献

1
Resection of an aneurysm of the abdominal aorta: reestablishment of the continuity by a preserved human arterial graft, with result after five months.腹主动脉瘤切除术:使用保存的人体动脉移植物重建连续性,术后五个月的结果。
AMA Arch Surg. 1952 Mar;64(3):405-8.
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THE BLEEDING COMPLICATIONS OF BLOOD TRANSFUSION.输血的出血并发症
Transfusion. 1965 Jan-Feb;5:1-5. doi: 10.1111/j.1537-2995.1965.tb01128.x.
3
Thromboplastic and fibrinolytic activity of the arteriosclerotic human aorta.动脉粥样硬化的人主动脉的促凝血和纤溶活性。
Nature. 1962 Jan 13;193:182-3. doi: 10.1038/193182a0.
4
The defibrination syndrome: clinical features and laboratory diagnosis.去纤维蛋白原综合征:临床特征与实验室诊断
Br J Haematol. 1967 Jul;13(4):528-49. doi: 10.1111/j.1365-2141.1967.tb00762.x.
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Multiple coagulation defects in association with dissecting aneurysm.
Arch Intern Med. 1967 May;119(5):522-6.
6
Diagnosis of ruptured aneurysm of the abdominal aorta.腹主动脉瘤破裂的诊断
N Engl J Med. 1967 Jun 8;276(23):1305-7. doi: 10.1056/NEJM196706082762307.
7
Contribution of abdominal aortic aneurysmectomy to prolongation of life.腹主动脉瘤切除术对延长生命的作用。
Ann Surg. 1966 Oct;164(4):678-99. doi: 10.1097/00000658-196610000-00014.
8
Studies on the adsorption and activation of the Hageman factor (factor XII) by collagen and elastin.关于胶原蛋白和弹性蛋白对哈格曼因子(因子XII)的吸附与激活的研究。
Thromb Diath Haemorrh. 1965 Nov 15;14(3-4):387-400.
9
Platelet counts with the Coulter counter.使用库尔特计数器进行血小板计数。
Am J Clin Pathol. 1965 Dec;44(6):678-88. doi: 10.1093/ajcp/44.6.678.
10
[Metabolism and localization of I 131-fibrinogen in chronic intravascular coagulation].[I 131-纤维蛋白原在慢性血管内凝血中的代谢与定位]
Schweiz Med Wochenschr. 1970 Nov 14;100(46):2001-3.