Smith P F
J Bacteriol. 1966 Jul;92(1):164-9. doi: 10.1128/jb.92.1.164-169.1966.
Smith, Paul F. (University of South Dakota, Vermillion). Comparative biosynthesis of ornithine and lysine by Mycoplasma and L forms. J. Bacteriol. 92:164-169. 1966.-Seven species of Mycoplasma, two L forms not requiring salt and their parent bacteria, and two yeasts were examined for enzymes involved in the biosynthesis of ornithine and lysine. All organisms tested, except two species of Mycoplasma and the yeasts, decarboxylated meso-alpha, epsilon-diaminopimelic acid. None of the Mycoplasma species or L forms was capable either of reducing alpha-aminoadipic acid to its semialdehyde or of incorporating alpha-aminoadipic acid-6-C(14) into lysine. All organisms, except the yeasts and Mycoplasma sp. caprine strain 14, acetylated glutamic acid, and all organisms possessed N(alpha)-acetyl-l-ornithine:2-oxo-glutarate aminotransferase activity. N(alpha)-acetylornithase activity was negligible in all organisms except Proteus and its L form. No transacetylation between acetylglutamic acid and ornithine, and vice versa, was demonstrable in any of the organisms. Mycoplasma species appear to possess the bacterial pathway to lysine. Ornithine does not appear to arise from glutamic acid.
史密斯，保罗·F.（南达科他大学，弗米利恩）。支原体和L型菌中鸟氨酸和赖氨酸的比较生物合成。《细菌学杂志》92:164 - 169。1966年。——对七种支原体、两种不需要盐的L型菌及其亲本细菌以及两种酵母进行了检测，以寻找参与鸟氨酸和赖氨酸生物合成的酶。除了两种支原体和酵母外，所有测试的生物体都能使内消旋-α，ε-二氨基庚二酸脱羧。没有一种支原体或L型菌能够将α-氨基己二酸还原为其半醛或将α-氨基己二酸-6-C(14)掺入赖氨酸中。除了酵母和支原体山羊菌株14外，所有生物体都能使谷氨酸乙酰化，并且所有生物体都具有N(α)-乙酰-L-鸟氨酸：2-氧代戊二酸转氨酶活性。除了变形杆菌及其L型菌外，所有生物体中的N(α)-乙酰鸟氨酸酶活性都可以忽略不计。在任何生物体中都未发现乙酰谷氨酸和鸟氨酸之间的转乙酰作用，反之亦然。支原体似乎具有细菌合成赖氨酸的途径。鸟氨酸似乎并非由谷氨酸产生。
