Joncas J H, Podoski M O, Pavilanis V
Can Med Assoc J. 1966 Aug 20;95(8):372-3.
Coxsackie A9 virus was identified by the authors during the fall of 1965 in Montreal in six children with fever and exanthem. Three of the six children were siblings. The exanthem was centrally distributed as described by Lerner et al. and consisted of discrete maculopapules 3 to 4 mm. in diameter. The viral agent was recovered and identified in tissue culture in five cases, while in the sixth Coxsackie type-A lesions were produced in suckling mice. Serological confirmation was obtained in two patients from whom sera were available. In contrast, no exanthem was observed in three older patients with a diagnosis of aseptic meningitis associated with Coxsackie A9 virus. In only one of 16 patients with Coxsackie B virus infection was an exanthem observed during the same period.The true incidence of Coxsackie A9-associated exanthems is difficult to determine because of the benign nature of the disease.
1965年秋季，作者在蒙特利尔确诊的6名发热出疹儿童中发现了柯萨奇A9病毒。这6名儿童中有3名是兄弟姐妹。皮疹呈中央分布，如勒纳等人所描述，由直径3至4毫米的散在斑丘疹组成。5例在组织培养中分离并鉴定出病毒病原体，而第6例在乳鼠中产生了A型柯萨奇病毒损伤。两名有血清样本的患者获得了血清学确诊。相比之下，3名诊断为与柯萨奇A9病毒相关的无菌性脑膜炎的年长患者未出现皮疹。同期，16例柯萨奇B病毒感染患者中仅1例出现皮疹。由于该疾病的良性性质，柯萨奇A9相关皮疹的真实发病率难以确定。
