Rotinberg P, Hefco V
Endocrinologie. 1977 Oct-Dec;15(4):257-61.
Medial hypothalamic isolation in the rat occurring under free food acces or after 24 hours starvation determines a significant increase in serum lipemia, serum esterified fatty acids and carcass fat. A significant rise in carcass fat was evident in rats made hyperphagic by medial hypothalamus isolation and maintained on limited food intake. It has been concluded that the VMH nuclei are involved in the control of the lipid metabolism primarily through the inhibitory effect exerted on the lateral hypothalamic parasympathetic area.
在自由获取食物或饥饿24小时后发生的大鼠内侧下丘脑隔离，会导致血清脂血症、血清酯化脂肪酸和胴体脂肪显著增加。通过内侧下丘脑隔离使大鼠食欲亢进并维持有限食物摄入量时，胴体脂肪显著增加。研究得出结论，VMH核主要通过对下丘脑外侧副交感神经区域施加抑制作用来参与脂质代谢的控制。
