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低位脊髓损伤截瘫患者分级手臂运动时的摄氧量和心输出量

Oxygen uptake and cardiac output in graded arm exercise in paraplegics with low level spinal lesions.

作者信息

Hjeltnes N

出版信息

Scand J Rehabil Med. 1977;9(3):107-13.

PMID:594687
Abstract

Oxygen uptake (V32), heart rate (fH) and cardiac output (Q, CO2-rebreathing method) were measured in 8 paraplegics with complete low level (Th6-Th12) lesions and in 1 paraplegic with a Th2 lesion during graded exercise performed on an arm ergometer. The submaximal work rates taxed about 50, 70 and 90% of the estimated functional capacity of the subjects. A linear relationship between the work rate and VO2 were assessed in the three tests. The increase of Q with increasing VO2 was accomplished by a considerable increase in fH accompanied by a slight increase in stroke volume (SV, calculated). Markedly low values of Q were found in 6 of the 9 subjects. The resulting high arterial-mixed venous blood oxygen content differences (calculated) as well as the high blood lactate concentrations (3.5-4.5 mM/l at 20-30 W and 8-11 mM/l after maximal exertion) indicate that the blood flow in the arm muscles was not adequate.

摘要

在手臂测力计上对8名低位(胸6 - 胸12)完全性损伤的截瘫患者和1名胸2损伤的截瘫患者进行分级运动时,测量了摄氧量(V̇O₂)、心率(fH)和心输出量(Q,采用二氧化碳重呼吸法)。次最大工作负荷约为受试者估计功能能力的50%、70%和90%。在三项测试中评估了工作负荷与V̇O₂之间的线性关系。随着V̇O₂增加,Q的增加是通过fH显著增加以及每搏输出量(SV,计算得出)略有增加来实现的。9名受试者中有6名的Q值明显较低。由此计算得出的动脉血与混合静脉血之间较高的氧含量差值以及较高的血乳酸浓度(20 - 30瓦时为3.5 - 4.5毫摩尔/升,最大运动后为8 - 11毫摩尔/升)表明,手臂肌肉的血流量不足。

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