Kaufman R E, Jones O G, Blount J H, Wiesner P J
Sex Transm Dis. 1977 Oct-Dec;4(4):135-9. doi: 10.1097/00007435-197710000-00003.
A retrospective questionnaire survey of a sample of 173 of the 360 cases of early congenital syphilis reported in 1972 revealed serious problems with diagnostic certainty, prevention, and treatment of congenital syphilis. Only 24 (13.9%) of the reported cases could be categorized as probably or definite cases based on criteria developed from a literature review. Forty percent of the mothers received no prenatal care and an additional 19% received no prenatal care until the third trimester. Initial and followup serologic testing was inadequate in those who received care. Eighty-three different penicillin treatment schedules were used in the treatment of 128 infants. Carefully reasoned diagnostic and therapeutic decision making about the management of congenital syphilis appears to be lacking.
对1972年报告的360例早期先天性梅毒病例中的173例进行回顾性问卷调查，结果显示先天性梅毒在诊断确定性、预防和治疗方面存在严重问题。根据文献综述制定的标准，报告的病例中只有24例（13.9%）可归类为可能或确诊病例。40%的母亲未接受产前护理，另有19%的母亲直到孕晚期才开始接受产前护理。接受护理的患者初始和随访血清学检测不足。在治疗128名婴儿时使用了83种不同的青霉素治疗方案。对于先天性梅毒的管理，似乎缺乏经过深思熟虑而做出的诊断和治疗决策。
