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曼氏血吸虫和日本血吸虫成虫中的三羧酸循环酶活性

Tricarboxylic acid cycle enzyme activities in adult Schistosoma mansoni and Schistosoma japonicum.

作者信息

Smith T M, Brown J N

出版信息

Trans R Soc Trop Med Hyg. 1977;71(4):329-30. doi: 10.1016/0035-9203(77)90112-2.

DOI:10.1016/0035-9203(77)90112-2
PMID:595083
Abstract

Reduced tricarboxylic acid cycle enzyme activities were found in paired adult Schistosoma mansoni and S. japonicum in comparison to those reported for S. mansoni cercariae (Coles, 1973). Succinate dehydrogenase activity, which has not been previously reported for either adult blood fluke, is more than twice as great in paired adult S. japonicum as in paired adult S. mansoni, but the activity is low in both species of adult worms. The similar low levels of tricarboxylic acid cycle enzyme activities which occur in adult S. mansoni and S. japonicum further substantiate the fact that anaerobic glycolysis is the major energy source in adults of both species.

摘要

与曼氏血吸虫尾蚴(科尔斯,1973年)相比,在配对的成年曼氏血吸虫和日本血吸虫中发现三羧酸循环酶活性降低。琥珀酸脱氢酶活性在配对的成年日本血吸虫中比在配对的成年曼氏血吸虫中高出两倍多,而此前两种成年血吸虫均未报告过该酶活性,但两种成年虫体中的该活性均较低。成年曼氏血吸虫和日本血吸虫中三羧酸循环酶活性的相似低水平进一步证实了无氧糖酵解是这两种成虫的主要能量来源这一事实。

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