曼氏血吸虫和日本血吸虫：成虫中葡萄糖-6-磷酸脱氢酶和6-磷酸葡萄糖酸脱氢酶活性的比较
Schistosoma mansoni and Schistosoma japonicum: comparison of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activities in adults.
作者信息
Smith T M, Brown J N
机构信息
Department of Biochemistry, University of Mississippi Medical Center, Jackson 39216.
出版信息
Comp Biochem Physiol B. 1977;56(3):351-2. doi: 10.1016/0305-0491(77)90028-1.
PMID:318249
Abstract
Glucose-6-phosphate dehydrogenase activity in paired adult Schistosoma mansoni is about twice as great as in paired adult Schistosoma japonicum. 2. 6-phosphogluconate dehydrogenase activity accounts for 25.8% of the measured production of reduced nicotinamide adenine dinucleotide phosphate (NADPH) in S. japonicum but only 8.6% of the measured production of NADPH in S. mansoni. 3. These data suggest a species difference in 6-phosphogluconate metabolism.
摘要
- 配对的成年曼氏血吸虫中葡萄糖-6-磷酸脱氢酶的活性约为配对的成年日本血吸虫中该酶活性的两倍。2. 在日本血吸虫中，6-磷酸葡萄糖酸脱氢酶的活性占所测还原型烟酰胺腺嘌呤二核苷酸磷酸（NADPH）生成量的25.8%，而在曼氏血吸虫中仅占所测NADPH生成量的8.6%。3. 这些数据表明6-磷酸葡萄糖酸代谢存在种间差异。
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