Purification and separation of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from human postmenopausal gonadotrophin (HMG). II. Preparation of biological apparently pure FSH by selective binding of the LH with an anti-HGG serum and subsequent chromatography.

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作者信息

Donini P, Puzzuoli D, D'Alessio I, Lunenfeld B, Eshkol A, Parlow A F

出版信息

Acta Endocrinol (Copenh). 1966 Jun;52(2):186-98.

PMID:5952830

Abstract

摘要

相似文献

Purification and separation of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from human postmenopausal gonadotrophin (HMG). II. Preparation of biological apparently pure FSH by selective binding of the LH with an anti-HGG serum and subsequent chromatography.

Acta Endocrinol (Copenh). 1966 Jun;52(2):186-98.

Purification and separation of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from human postmenopausal gonadotrophin (HMG). I. Separation of FSH and LH by electrophoresis, chromatography and gel filtration procedures.从人绝经后促性腺激素（HMG）中纯化和分离促卵泡激素（FSH）和促黄体生成素（LH）。I. 通过电泳、色谱法和凝胶过滤法分离FSH和LH

Acta Endocrinol (Copenh). 1966 Jun;52(2):169-85. doi: 10.1530/acta.0.0520169.

A comparison of biologic and immunologic potency estimates of human luteinizing (LH) and follicle stimulating (FSH) hormones.

Acta Endocrinol Suppl (Copenh). 1969;142:301-23.

Bioassay of antigonadotrophic sera. 2. Assay of the human chorionic gonadotrophin (HCG) and luteinising hormone (LH) neutralising potencies.抗促性腺激素血清的生物测定。2. 人绒毛膜促性腺激素（HCG）和促黄体生成素（LH）中和效价的测定。

Acta Endocrinol (Copenh). 1968 Oct;59(2):261-76.

Bioassay of antigonadotrophic sera. 3. Assay of the human follicle stimulating hormone (FSH) neutralising potency.抗促性腺激素血清的生物测定。3. 人卵泡刺激素（FSH）中和效价的测定。

Acta Endocrinol (Copenh). 1968 Oct;59(2):277-97.

[Determination of the gonadotropin content of preparations of pregnant mare's serum (PMSG). 2. Action equivalence of PMSG in bioassays for follicle-stimulating hormone (FSH) and luteinizing hormone (LH) or human chorionic gonadotropins (HCG), critical evaluation of methods].[孕马血清制剂中促性腺激素含量的测定。2. 孕马血清促性腺激素在促卵泡激素（FSH）、促黄体生成素（LH）或人绒毛膜促性腺激素（HCG）生物测定中的作用等效性，方法的批判性评价]

Arch Exp Veterinarmed. 1983 Sep;37(5):767-75.

[Effect of concentration of circulating luteinizing hormone in late-follicle phase on the outcome of in vitro fertilization for normogonadotrophic women].[卵泡晚期循环黄体生成素浓度对正常促性腺激素女性体外受精结局的影响]

Zhonghua Nan Ke Xue. 2004 Dec;10(12):912-5.

Clinical effects of ovulation induction with recombinant follicle-stimulating hormone supplemented with recombinant luteinizing hormone or low-dose recombinant human chorionic gonadotropin in the midfollicular phase in microdose cycles in poor responders.在微刺激周期中，于卵泡中期使用重组促卵泡激素联合重组促黄体生成素或低剂量重组人绒毛膜促性腺激素进行促排卵对卵巢低反应者的临床效果。

Fertil Steril. 2007 Sep;88(3):665-9. doi: 10.1016/j.fertnstert.2006.11.150. Epub 2007 Feb 12.

[Determination of gonadotropic valency of preparations from pregnant mare's serum (PMSG). 3. Determination of the "PMSG-Substandard-Dessau" activity in follicle-stimulating hormone (FSH) and luteinizing hormone (LH) bioassays].[孕马血清（PMSG）制剂促性腺活性的测定。3. 在促卵泡激素（FSH）和促黄体生成素（LH）生物测定中“PMSG-德绍标准以下品”活性的测定]

Arch Exp Veterinarmed. 1983 Nov;37(6):801-6.

[Experiment in purifying FSH using anti-HCH serum].[使用抗六氯环己烷血清纯化促卵泡激素的实验]

Nihon Sanka Fujinka Gakkai Zasshi. 1969 Feb;21(2):163-72.

引用本文的文献

The influence of the pharmaceutical industry on the development of gonadotrophins and ovarian stimulation protocols in assisted reproductive technologies.制药行业对辅助生殖技术中促性腺激素及卵巢刺激方案发展的影响。

Front Endocrinol (Lausanne). 2025 Apr 4;16:1536844. doi: 10.3389/fendo.2025.1536844. eCollection 2025.

The Development of Gonadotropins for Clinical Use in the Treatment of Infertility.用于治疗不孕症的临床促性腺激素的发展

Front Endocrinol (Lausanne). 2019 Jul 3;10:429. doi: 10.3389/fendo.2019.00429. eCollection 2019.

Modulation of Gonadotropins Activity by Antibodies.抗体对促性腺激素活性的调节

Front Endocrinol (Lausanne). 2019 Feb 18;10:15. doi: 10.3389/fendo.2019.00015. eCollection 2019.

Mixed protocols: multiple ratios of FSH and LH bioactivity using highly purified, human-derived FSH (BRAVELLE) and highly purified hMG (MENOPUR) are unaltered by mixing together in the same syringe.混合方案：使用高度纯化的人源促卵泡激素（BRAVELLE）和高度纯化的人绝经期促性腺激素（MENOPUR），将促卵泡激素（FSH）和促黄体生成素（LH）生物活性的多种比例混合于同一注射器中，其活性不变。

Reprod Biol Endocrinol. 2005 Nov 9;3:61. doi: 10.1186/1477-7827-3-61.

Highly purified human-derived follicle-stimulating hormone (Bravelle) has equivalent efficacy to follitropin-beta (Follistim) in infertile women undergoing in vitro fertilization.高纯度人源促卵泡激素（Bravelle）在接受体外受精的不孕女性中与促卵泡素β（Follistim）具有同等疗效。

Reprod Biol Endocrinol. 2003 Oct 3;1:63. doi: 10.1186/1477-7827-1-63.

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