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[强毒型和疫苗型新城疫毒株抗原特性的免疫电泳研究]

[Immunoelectrophoretic studies of the antigenic properties of virulent and vaccinal Newcastle strains].

作者信息

Danchev P

出版信息

Vet Med Nauki. 1977;14(6):47-52.

PMID:595372
Abstract

Studied were immunoelectrophoretically the antigenic properties of 16 virulent and 4 vaccinal strains of the Newcastle disease virus--B1, La Sota, Komarov, and Roakin. Results showed that all virulent strains isolated in the course of 5 years had the same antigenic components as compared both to each other and to the vaccinal strains. This similarity was manifested by the presence of a clearly expressed precipitation line found with all strains in one and the same place of the immunoelectrophoregrams. It was assumed on the basis of the results obtained that there is no variation in the antigenic structure of the Newcastle disease virus. This confirmed the appropriateness in using the vaccinal strains B1, La Sota, Komarov, and Roakin in the active prophylaxis of birds against Newcastle disease.

摘要

对新城疫病毒的16株强毒株和4株疫苗株——B1、La Sota、科马罗夫和罗阿金进行了免疫电泳抗原特性研究。结果表明,在5年期间分离出的所有强毒株,彼此之间以及与疫苗株相比,具有相同的抗原成分。这种相似性表现为在免疫电泳图谱的同一位置,所有毒株都出现一条清晰的沉淀线。根据所获结果推测,新城疫病毒的抗原结构没有变化。这证实了使用疫苗株B1、La Sota、科马罗夫和罗阿金对禽类进行新城疫主动预防的适宜性。

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