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[通过喷雾法使用B1和La Sota株疫苗对肉鸡进行新城疫免疫计划的研究]

[Study of an immunization plan for broilers via the spray method against Newcastle disease using vaccines from the Bl and La Sota strains].

作者信息

Dimitrov N, Khadzhiev G, Cholakova R, Kirechiev G

出版信息

Vet Med Nauki. 1976;13(9):53-8.

PMID:1025847
Abstract

Studied was the immunization pattern against Newcastle disease in birds with the use of a spray method on broilers obtained congenitally from their mothers, having antihemagglutinins. All birds on one of the premises ( a total of 14, 000) were vaccinated when 5 days old with a liquid vaccine of strain B1 (one fourth dose per bird) using the Dutch pulverizing apparatus Flox-10 -- group I. Other 14,000 birds of another of the premises of the same batch were treated at the same age with the same dose via the same route of application of a liquid vaccine of the La Sota strain --group II. All birds of the two groups were revaccinated in the same way at the age of 25 days with a vaccine of the La Sota strain at the rate of a whole dose per bird. The birds were kept under equal conditons of feeding and management. It was found that they built immunity which protected them fully from Newcastle disease up to the end of the fattening period (2 months). This was demonstrated by the test for establishing resistance to a control infection with a highly virulent strain of the Newcastle disease virus (challenge) as well as serologically by the hemagglutination inhibition reaction. At the slaughter by the end of the fattening period all period all birds of the two groups sshowed almost equal average body weight, however, those of group I manifested 0.97 per cent lower mortality rate and lower forage intake per kg weight (by 23 g on an average).

摘要

研究了对从先天带有抗血凝素的母鸡获得的肉鸡采用喷雾法进行新城疫免疫接种的模式。在一栋鸡舍(共14000只)中的所有鸡在5日龄时,使用荷兰的Flox - 10雾化设备,用B1株液体疫苗(每只鸡四分之一剂量)进行免疫接种——第一组。同一批次另一栋鸡舍的另外14000只鸡在相同年龄通过相同接种途径用相同剂量的La Sota株液体疫苗进行处理——第二组。两组所有鸡在25日龄时都以每只鸡一整剂量的La Sota株疫苗以相同方式进行再次免疫接种。这些鸡在相同的饲养和管理条件下饲养。结果发现,它们产生了免疫力,在育肥期(2个月)结束前能完全保护它们免受新城疫感染。这通过用新城疫病毒强毒株进行对照感染(攻毒)的抗性试验以及通过血凝抑制反应进行血清学检测得到了证明。在育肥期结束屠宰时,两组所有鸡的平均体重几乎相等,然而,第一组的死亡率低0.97%,每千克体重的采食量也较低(平均低23克)。

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