5-氟胞嘧啶-2-¹⁴C和胞嘧啶-¹⁴C在大鼠体内的代谢以及5-氟胞嘧啶-2-¹⁴C在人体内的分布。 - Suppr

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The metabolism of 5-fluorocytosine-2-14-C and of cytosine-14-C in the rat and the disposition of 5-fluorocytosine-2-14-C in man.

作者信息

Koechlin B A, Rubio F, Palmer S, Gabriel T, Duschinsky R

出版信息

Biochem Pharmacol. 1966 Apr;15(4):435-46. doi: 10.1016/0006-2952(66)90254-1.

DOI:10.1016/0006-2952(66)90254-1

PMID:5955812

Abstract

摘要

相似文献

The metabolism of 5-fluorocytosine-2-14-C and of cytosine-14-C in the rat and the disposition of 5-fluorocytosine-2-14-C in man.

Biochem Pharmacol. 1966 Apr;15(4):435-46. doi: 10.1016/0006-2952(66)90254-1.

The kinetics of 5-fluorocytosine elimination in man.

Aust N Z J Med. 1972 May;2(2):153-8. doi: 10.1111/j.1445-5994.1972.tb03925.x.

Catabolism of 14C-thiazole-labeled oxythiamine and its effects on thiamine catabolism in the rat.

J Nutr. 1968 Oct;96(2):206-14. doi: 10.1093/jn/96.2.206.

4-Methylthiazole-5-acetic acid--a urinary metabolite of thiamine.

J Nutr. 1968 Dec;96(4):445-9. doi: 10.1093/jn/96.4.445.

Fluorometric measurement of 5-fluorocytosine in biological fluids.

J Pharm Sci. 1973 May;62(5):828-9. doi: 10.1002/jps.2600620531.

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Br Med J. 1971 Mar 13;1(5749):577-9. doi: 10.1136/bmj.1.5749.577.

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Ann Intern Med. 1972 Jan;76(1):15-22. doi: 10.7326/0003-4819-76-1-15.

Biological activity and excreation of the riboflavin analogues, 6,7-dimethyl-9-(omega-carboxyalkyl)-isoalloxazines in rats.

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Clinical pharmacokinetics of systemic antifungal drugs.

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The metabolism of 5-fluorocytosine-2-14-C and of cytosine-14-C in the rat and the disposition of 5-fluorocytosine-2-14-C in man.

作者信息

Koechlin B A, Rubio F, Palmer S, Gabriel T, Duschinsky R

出版信息

Biochem Pharmacol. 1966 Apr;15(4):435-46. doi: 10.1016/0006-2952(66)90254-1.

DOI:10.1016/0006-2952(66)90254-1

PMID:5955812

Abstract

摘要

相似文献

The metabolism of 5-fluorocytosine-2-14-C and of cytosine-14-C in the rat and the disposition of 5-fluorocytosine-2-14-C in man.

Biochem Pharmacol. 1966 Apr;15(4):435-46. doi: 10.1016/0006-2952(66)90254-1.

The kinetics of 5-fluorocytosine elimination in man.

Aust N Z J Med. 1972 May;2(2):153-8. doi: 10.1111/j.1445-5994.1972.tb03925.x.

Catabolism of 14C-thiazole-labeled oxythiamine and its effects on thiamine catabolism in the rat.

J Nutr. 1968 Oct;96(2):206-14. doi: 10.1093/jn/96.2.206.

4-Methylthiazole-5-acetic acid--a urinary metabolite of thiamine.

J Nutr. 1968 Dec;96(4):445-9. doi: 10.1093/jn/96.4.445.

Fluorometric measurement of 5-fluorocytosine in biological fluids.

J Pharm Sci. 1973 May;62(5):828-9. doi: 10.1002/jps.2600620531.

Cytosine deaminase/5-fluorocytosine-based vaccination against liver tumors: evidence of distant bystander effect.

J Natl Cancer Inst. 1999 Dec 1;91(23):2014-9. doi: 10.1093/jnci/91.23.2014.

5-fluorocytosine and urinary candidiasis.

Br Med J. 1971 Mar 13;1(5749):577-9. doi: 10.1136/bmj.1.5749.577.

Adenovirus mediated cytosine deaminase gene transduction and 5-fluorocytosine therapy sensitizes mouse prostate cancer cells to irradiation.

J Urol. 2000 Dec;164(6):2173-7.

5-fluorocytosine: an oral antifungal compound. A report on clinical and laboratory experience.

Ann Intern Med. 1972 Jan;76(1):15-22. doi: 10.7326/0003-4819-76-1-15.

Biological activity and excreation of the riboflavin analogues, 6,7-dimethyl-9-(omega-carboxyalkyl)-isoalloxazines in rats.

J Nutr. 1969 Mar;97(3):307-10. doi: 10.1093/jn/97.3.307.

引用本文的文献

Aspergillus Niger thermostable Cytosine deaminase-dextran conjugates with enhanced structure stability, proteolytic resistance, and Antiproliferative activity.

BMC Microbiol. 2023 Jan 10;23(1):9. doi: 10.1186/s12866-023-02754-8.

Improved cytotoxic effects of Salmonella-producing cytosine deaminase in tumour cells.

Microb Biotechnol. 2015 Jan;8(1):169-76. doi: 10.1111/1751-7915.12153. Epub 2014 Sep 16.

Inhibitory effect of pulmonary carcinoma by adenovirus-mediated CD/UPRT gene.

J Huazhong Univ Sci Technolog Med Sci. 2006;26(5):591-3. doi: 10.1007/s11596-006-0529-0.

Proc Natl Acad Sci U S A. 1994 Aug 16;91(17):8302-6. doi: 10.1073/pnas.91.17.8302.

Peritoneal clearance of amphotericin B and 5-fluorocytosine.

West J Med. 1980 Aug;133(2):157-60.

5-fluorocytosine susceptibility of pathogenic fungi in the presence of allopurinol: potential for improving the therapeutic index of 5-fluorocytosine.

Antimicrob Agents Chemother. 1983 Sep;24(3):448-9. doi: 10.1128/AAC.24.3.448.

Improved procedure for determination of flucytosine in human blood plasma by high-pressure liquid chromatography.

Antimicrob Agents Chemother. 1984 Sep;26(3):303-5. doi: 10.1128/AAC.26.3.303.

Candida esophagitis.

Dig Dis Sci. 1983 Apr;28(4):365-70. doi: 10.1007/BF01324956.

Clinical pharmacokinetics of systemic antifungal drugs.

Clin Pharmacokinet. 1983 Jan-Feb;8(1):17-42. doi: 10.2165/00003088-198308010-00002.

Chemotherapy of experimental endogenous Candida albicans endophthalmitis.

Trans Am Ophthalmol Soc. 1980;78:846-95.