von Eisenhart-Rothe B, Ganschow I, Dominka T, Kühnl P
Abteilung für Transfusionsmedizin und Transplantationsimmunologie, Chirurgische Universitätsklinik, Hamburg-Eppendorf, BRD.
Beitr Infusionsther. 1992;30:131-5.
In this study, we compared the ability of serum and of 5 additive solutions for the liquid storage of red blood cells to preserve the cellular contents of 2,3-BPG and the adenylate nucleotides ATP, ADP and AMP. As to the adenylates, PAGGS-M showed the best results. However, the difference to SAG-M was significant only after 7 weeks. On the other hand, serum appears to be the best medium for the conservation of 2,3-BPG. Between the 1st and 3rd week of storage, the decrease of 2,3-BPG was somewhat slower in PAGGS-M and SAG-M compared with the other 3 additive solutions.
在本研究中,我们比较了血清以及用于红细胞液体保存的5种添加剂溶液保存2,3-二磷酸甘油酸(2,3-BPG)和腺苷酸三磷酸(ATP)、二磷酸腺苷(ADP)及一磷酸腺苷(AMP)细胞内成分的能力。对于腺苷酸,聚乙二醇化腺嘌呤-葡萄糖-腺嘌呤-甘露醇-蔗糖(PAGGS-M)表现出最佳结果。然而,仅在7周后其与生理盐水-腺嘌呤-葡萄糖-甘露醇(SAG-M)的差异才显著。另一方面,血清似乎是保存2,3-BPG的最佳介质。在储存的第1周和第3周之间,与其他3种添加剂溶液相比,PAGGS-M和SAG-M中2,3-BPG的减少略显缓慢。