猫迷走神经传入刺激后某些心血管参数及交感神经活动的变化

Changes of certain cardio-vascular parameters and the sympathetic nervous activity upon afferent vagal stimulation in cats.

作者信息

Mileva S

出版信息

Acta Physiol Pharmacol Bulg. 1977;3(2):54-61.

Abstract

Afferent stimulation of the cervical vagus in cats for 5 s upon bilateral vagotomy reduces systemic blood pressure by 15--50 percent. The maximum of this depressor reaction occurs 10--15 s after the beginning of the stimulation, its latency being 2--3 s. The decrease in the blood pressure is preceded by inhibition of the electrical activity of some preganglionic (n. splanchnicus) and postganglionic (n. cardiacus and n. renalis) sympathetic nerves with 100--200 ms latency. During the maximum pressure decrease activity appears in the above-mentioned nerves, afterwards the pressure begins to rise until its normalization. In addition to the decrease in systemic blood pressure changes are also observed in other cardio-vascular parameters, namely, decrease in the pressure in the left ventricle, decrease in the contractile force of the heart (dp/dt max) and of the heart rate.

摘要

在双侧迷走神经切断术后，对猫的颈迷走神经进行5秒的传入刺激，可使全身血压降低15%至50%。这种降压反应的最大值出现在刺激开始后10至15秒，其潜伏期为2至3秒。血压下降之前，一些节前（内脏神经）和节后（心神经和肾神经）交感神经的电活动受到抑制，潜伏期为100至200毫秒。在血压最大降幅期间，上述神经出现活动，随后血压开始上升直至恢复正常。除了全身血压下降外，其他心血管参数也出现变化，即左心室压力降低、心脏收缩力（dp/dt max）和心率降低。